Kdm6a deficiency restricted to mouse hematopoietic cells causes an age- and sex-dependent myelodysplastic syndrome-like phenotype

Ling Tian; Monique Chavez; Gue Su Chang; Nichole M. Helton; Casey D. S. Katerndahl; Christopher A. Miller; Lukas D. Wartman

doi:10.1371/journal.pone.0255706

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Peer-reviewed

Research Article

Kdm6a deficiency restricted to mouse hematopoietic cells causes an age- and sex-dependent myelodysplastic syndrome-like phenotype

Ling Tian ,

Contributed equally to this work with: Ling Tian, Monique Chavez

Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, United States of America
⨯
Monique Chavez ,

Contributed equally to this work with: Ling Tian, Monique Chavez

Roles Formal analysis, Investigation, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, United States of America

https://orcid.org/0000-0002-5317-3867

⨯
Gue Su Chang,

Roles Data curation, Formal analysis, Software, Visualization

Affiliation McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, United States of America
⨯
Nichole M. Helton,

Roles Investigation

Affiliation Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, United States of America
⨯
Casey D. S. Katerndahl,

Roles Writing – original draft, Writing – review & editing

Affiliation Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, United States of America
⨯
Christopher A. Miller,

Roles Data curation, Funding acquisition, Software

Affiliations Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, United States of America, McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, United States of America
⨯
Lukas D. Wartman

Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: lwartman@wustl.edu

Affiliation Division of Oncology, Department of Internal Medicine, Washington University School of Medicine, St Louis, MO, United States of America
⨯

Kdm6a deficiency restricted to mouse hematopoietic cells causes an age- and sex-dependent myelodysplastic syndrome-like phenotype

Ling Tian,
Monique Chavez,
Gue Su Chang,
Nichole M. Helton,
Casey D. S. Katerndahl,
Christopher A. Miller,
Lukas D. Wartman

Published: November 15, 2021
https://doi.org/10.1371/journal.pone.0255706

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