Targeted capture sequencing identifies genetic variations of GRK4 and RDH8 in Han Chinese with essential hypertension in Xinjiang

Wenxi Jiang; Xizi Wang; Ronghui Li; Panpan Wang; Guangle Shan; Xiaodong Jia; Mingliang Gu

doi:10.1371/journal.pone.0255311

Loading metrics

Open Access

Peer-reviewed

Research Article

Targeted capture sequencing identifies genetic variations of GRK4 and RDH8 in Han Chinese with essential hypertension in Xinjiang

Wenxi Jiang ,

Contributed equally to this work with: Wenxi Jiang, Xizi Wang

Roles Conceptualization, Data curation, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliation Department of Medicine, The Fifth Affiliated Hospital of Xinjiang Medical University, Urumqi, China
⨯
Xizi Wang ,

Contributed equally to this work with: Wenxi Jiang, Xizi Wang

Roles Formal analysis, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliation Joint Laboratory for Translational Medicine Research, Beijing Institute of Genomics, Chinese Academy of Sciences & Liaocheng People’s Hospital, Liaocheng, China
⨯
Ronghui Li,

Roles Formal analysis, Methodology

Affiliation CAS Key Laboratory of Genome Science and Information, Beijing Institute of Genomics, Chinese Academy of Sciences (CAS), Beijing, China
⨯
Panpan Wang,

Roles Data curation, Investigation, Methodology

Affiliation CAS Key Laboratory of Genome Science and Information, Beijing Institute of Genomics, Chinese Academy of Sciences (CAS), Beijing, China
⨯
Guangle Shan,

Roles Formal analysis, Methodology

Affiliation CAS Key Laboratory of Genome Science and Information, Beijing Institute of Genomics, Chinese Academy of Sciences (CAS), Beijing, China
⨯
Xiaodong Jia,

Roles Data curation, Methodology

Affiliation CAS Key Laboratory of Genome Science and Information, Beijing Institute of Genomics, Chinese Academy of Sciences (CAS), Beijing, China
⨯
Mingliang Gu

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

* E-mail: minglianggu@hotmail.com, guml@big.ac.cn

Affiliations Joint Laboratory for Translational Medicine Research, Beijing Institute of Genomics, Chinese Academy of Sciences & Liaocheng People’s Hospital, Liaocheng, China, CAS Key Laboratory of Genome Science and Information, Beijing Institute of Genomics, Chinese Academy of Sciences (CAS), Beijing, China
⨯

Targeted capture sequencing identifies genetic variations of GRK4 and RDH8 in Han Chinese with essential hypertension in Xinjiang

Wenxi Jiang,
Xizi Wang,
Ronghui Li,
Panpan Wang,
Guangle Shan,
Xiaodong Jia,
Mingliang Gu

Published: July 23, 2021
https://doi.org/10.1371/journal.pone.0255311

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Hypertension
Is the Subject Area "Hypertension" applicable to this article?

Thanks for your feedback.
Vitamin A
Is the Subject Area "Vitamin A" applicable to this article?

Thanks for your feedback.
Single nucleotide polymorphisms
Is the Subject Area "Single nucleotide polymorphisms" applicable to this article?

Thanks for your feedback.
Blood pressure
Is the Subject Area "Blood pressure" applicable to this article?

Thanks for your feedback.
RNA structure
Is the Subject Area "RNA structure" applicable to this article?

Thanks for your feedback.
Gene sequencing
Is the Subject Area "Gene sequencing" applicable to this article?

Thanks for your feedback.
Dopamine
Is the Subject Area "Dopamine" applicable to this article?

Thanks for your feedback.
Pathogenesis
Is the Subject Area "Pathogenesis" applicable to this article?

Thanks for your feedback.