Archival bone marrow smears are useful in targeted next-generation sequencing for diagnosing myeloid neoplasms

Daichi Sadato; Chizuko Hirama; Ai Kaiho-Soma; Ayaka Yamaguchi; Hiroko Kogure; Sonomi Takakuwa; Mina Ogawa; Noriko Doki; Kazuteru Ohashi; Hironori Harada; Keisuke Oboki; Yuka Harada

doi:10.1371/journal.pone.0255257

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Open Access

Peer-reviewed

Research Article

Archival bone marrow smears are useful in targeted next-generation sequencing for diagnosing myeloid neoplasms

Daichi Sadato ,

Contributed equally to this work with: Daichi Sadato, Chizuko Hirama

Roles Conceptualization, Data curation, Methodology, Writing – original draft

Affiliations Clinical Research Center, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan, Center for Medical Research Cooperation, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan

https://orcid.org/0000-0002-3873-8268

⨯
Chizuko Hirama ,

Contributed equally to this work with: Daichi Sadato, Chizuko Hirama

Roles Conceptualization, Investigation, Methodology

Affiliations Clinical Research Center, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan, Center for Medical Research Cooperation, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
⨯
Ai Kaiho-Soma,

Roles Investigation, Methodology

Affiliations Clinical Research Center, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan, Center for Medical Research Cooperation, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
⨯
Ayaka Yamaguchi,

Roles Investigation

Affiliation Clinical Research Center, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan
⨯
Hiroko Kogure,

Roles Investigation

Affiliation Clinical Research Center, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan
⨯
Sonomi Takakuwa,

Roles Investigation

Affiliation Clinical Research Center, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan
⨯
Mina Ogawa,

Roles Investigation

Affiliations Clinical Research Center, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan, Center for Medical Research Cooperation, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
⨯
Noriko Doki,

Roles Resources

Affiliation Division of Hematology, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan
⨯
Kazuteru Ohashi,

Roles Resources

Affiliation Division of Hematology, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan
⨯
Hironori Harada,

Roles Supervision

Affiliations Division of Hematology, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan, Laboratory of Oncology, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan
⨯
Keisuke Oboki,

Roles Supervision

Affiliation Center for Medical Research Cooperation, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan
⨯
Yuka Harada

Roles Conceptualization, Data curation, Funding acquisition, Supervision, Writing – original draft

* E-mail: yharada@cick.jp

Affiliation Clinical Research Center, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan
⨯

Archival bone marrow smears are useful in targeted next-generation sequencing for diagnosing myeloid neoplasms

Daichi Sadato,
Chizuko Hirama,
Ai Kaiho-Soma,
Ayaka Yamaguchi,
Hiroko Kogure,
Sonomi Takakuwa,
Mina Ogawa,
Noriko Doki,
Kazuteru Ohashi,
Hironori Harada

Published: July 23, 2021
https://doi.org/10.1371/journal.pone.0255257

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