SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts

Rafail Nikolaos Tasakis; Georgios Samaras; Anna Jamison; Michelle Lee; Alexandra Paulus; Gabrielle Whitehouse; Laurent Verkoczy; F. Nina Papavasiliou; Marilyn Diaz

doi:10.1371/journal.pone.0255169

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Open Access

Peer-reviewed

Research Article

SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts

Rafail Nikolaos Tasakis,

Roles Conceptualization, Data curation, Methodology, Supervision, Validation, Writing – review & editing

Affiliations Division of Immune Diversity, German Cancer Research Center (DKFZ), Heidelberg, Germany, Faculty of Biosciences, University of Heidelberg, Heidelberg, Germany

https://orcid.org/0000-0003-2650-2220

⨯
Georgios Samaras,

Roles Data curation, Writing – review & editing

Affiliations Division of Immune Diversity, German Cancer Research Center (DKFZ), Heidelberg, Germany, Program of Translational Medical Research, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany

https://orcid.org/0000-0002-1538-0048

⨯
Anna Jamison ,

Contributed equally to this work with: Anna Jamison, Michelle Lee, Alexandra Paulus, Gabrielle Whitehouse

Roles Formal analysis, Validation, Visualization

Affiliation The Nightingale-Bamford School, New York, NY, United States of America
⨯
Michelle Lee ,

Contributed equally to this work with: Anna Jamison, Michelle Lee, Alexandra Paulus, Gabrielle Whitehouse

Roles Formal analysis, Validation, Visualization

Affiliation Cornell University, Ithaca, NY, United States of America
⨯
Alexandra Paulus ,

Contributed equally to this work with: Anna Jamison, Michelle Lee, Alexandra Paulus, Gabrielle Whitehouse

Roles Formal analysis, Validation, Visualization

Affiliation The Nightingale-Bamford School, New York, NY, United States of America

https://orcid.org/0000-0003-0986-2777

⨯
Gabrielle Whitehouse ,

Contributed equally to this work with: Anna Jamison, Michelle Lee, Alexandra Paulus, Gabrielle Whitehouse

Roles Formal analysis, Validation, Visualization

Affiliation The Nightingale-Bamford School, New York, NY, United States of America

https://orcid.org/0000-0002-8186-3574

⨯
Laurent Verkoczy ,

Roles Formal analysis, Supervision, Writing – original draft, Writing – review & editing

* E-mail: mdiaz@SDBRI.ORG (MD); lverkoczy@SDBRI.ORG (LV); n.papavasiliou@dkfz-heidelberg.de (FNP)

Affiliation San Diego Biomedical Research Institute (SDBRI), San Diego, CA, United States of America

https://orcid.org/0000-0001-7497-6645

⨯
F. Nina Papavasiliou ,

Roles Project administration, Writing – original draft, Writing – review & editing

* E-mail: mdiaz@SDBRI.ORG (MD); lverkoczy@SDBRI.ORG (LV); n.papavasiliou@dkfz-heidelberg.de (FNP)

Affiliation Division of Immune Diversity, German Cancer Research Center (DKFZ), Heidelberg, Germany

https://orcid.org/0000-0002-5971-7909

⨯
Marilyn Diaz

Roles Writing – original draft, Writing – review & editing

* E-mail: mdiaz@SDBRI.ORG (MD); lverkoczy@SDBRI.ORG (LV); n.papavasiliou@dkfz-heidelberg.de (FNP)

Current address: Applied Biomedical Science Institute, San Diego, CA, United States of America

Affiliation San Diego Biomedical Research Institute (SDBRI), San Diego, CA, United States of America

https://orcid.org/0000-0002-3046-2746

⨯

SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts

Rafail Nikolaos Tasakis,
Georgios Samaras,
Anna Jamison,
Michelle Lee,
Alexandra Paulus,
Gabrielle Whitehouse,
Laurent Verkoczy,
F. Nina Papavasiliou,
Marilyn Diaz

Published: July 23, 2021
https://doi.org/10.1371/journal.pone.0255169

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