Trisomy 21-associated increases in chromosomal instability are unmasked by comparing isogenic trisomic/disomic leukocytes from people with mosaic Down syndrome

• Kelly Rafferty,

  Roles Data curation, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliations Department of Human & Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America, Department of Pathology, Virginia Commonwealth University, Richmond, Virginia, United States of America

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• Kellie J. Archer,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Division of Biostatistics, College of Public Health, The Ohio State University, Columbus, Ohio, United States of America

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• Kristi Turner,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Pathology, Virginia Commonwealth University, Richmond, Virginia, United States of America

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• Ruth Brown,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Department of Psychiatry, Virginia Commonwealth University, Richmond, Virginia, United States of America

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• Colleen Jackson-Cook

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Writing – original draft, Writing – review & editing

  * E-mail: colleen.jackson-cook@vcuhealth.org

  Affiliations Department of Human & Molecular Genetics, Virginia Commonwealth University, Richmond, Virginia, United States of America, Department of Pathology, Virginia Commonwealth University, Richmond, Virginia, United States of America

  https://orcid.org/0000-0002-3261-909X

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