Computational modelling unveils how epiblast remodelling and positioning rely on trophectoderm morphogenesis during mouse implantation

Joel Dokmegang; Moi Hoon Yap; Liangxiu Han; Matteo Cavaliere; René Doursat

doi:10.1371/journal.pone.0254763

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Open Access

Peer-reviewed

Research Article

Computational modelling unveils how epiblast remodelling and positioning rely on trophectoderm morphogenesis during mouse implantation

Joel Dokmegang ,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: joel.dokmegang-kassap@stu.mmu.ac.uk (JD); m.cavaliere@mmu.ac.uk (MC)

Affiliations Centre for Advanced Computational Science (CfACS), Manchester Metropolitan University, Manchester, United Kingdom, NSF-Simons Center for Quantitative Biology, Northwestern University, Evanston, Illinois, United States of America

https://orcid.org/0000-0001-9953-7913

⨯
Moi Hoon Yap,

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft

Affiliation Centre for Advanced Computational Science (CfACS), Manchester Metropolitan University, Manchester, United Kingdom

https://orcid.org/0000-0001-7681-4287

⨯
Liangxiu Han,

Roles Funding acquisition, Investigation, Project administration, Supervision, Writing – original draft

Affiliation Centre for Advanced Computational Science (CfACS), Manchester Metropolitan University, Manchester, United Kingdom

https://orcid.org/0000-0003-2491-7473

⨯
Matteo Cavaliere ,

Roles Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: joel.dokmegang-kassap@stu.mmu.ac.uk (JD); m.cavaliere@mmu.ac.uk (MC)

Affiliation Centre for Advanced Computational Science (CfACS), Manchester Metropolitan University, Manchester, United Kingdom
⨯
René Doursat

Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft

Affiliations Centre for Advanced Computational Science (CfACS), Manchester Metropolitan University, Manchester, United Kingdom, Complex Systems Institute, Paris Ile-de-France (ISC-PIF), National Centre for Scientific Research (CNRS), Paris, France

https://orcid.org/0000-0001-6682-4887

⨯

Computational modelling unveils how epiblast remodelling and positioning rely on trophectoderm morphogenesis during mouse implantation

Joel Dokmegang,
Moi Hoon Yap,
Liangxiu Han,
Matteo Cavaliere,
René Doursat

Published: July 28, 2021
https://doi.org/10.1371/journal.pone.0254763

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