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Open Access
Peer-reviewed
Research Article
Coupling proteomics and metabolomics for the unsupervised identification of protein–metabolite interactions in Chaetomium thermophilum
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Yuanyue Li,
Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing
Current address: NIH West Coast Metabolomics Center, University of California Davis, Davis, CA, United States of America
Affiliation Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
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Michael Kuhn ,
Roles Conceptualization, Formal analysis, Supervision, Writing – original draft, Writing – review & editing
* E-mail: mkuhn@embl.de (MK); Anne-Claude.Gavin@unige.ch (A-CG); bork@embl.de (PB)
Affiliation Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
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Joanna Zukowska-Kasprzyk,
Roles Investigation
Affiliation Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
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Marco L. Hennrich,
Roles Investigation
Current address: Cellzome GmbH, Molecular Discovery Research, GlaxoSmithKline, Heidelberg, Germany
Affiliation Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
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Panagiotis L. Kastritis,
Roles Investigation
Current address: Martin-Luther-Universität Halle-Wittenberg, Halle, Germany
Affiliation Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
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Francis J. O’Reilly,
Roles Investigation
Current address: Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, Berlin, Germany
Affiliation Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
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Prasad Phapale,
Roles Investigation
Affiliation Metabolomics Core Facility, European Molecular Biology Laboratory, Heidelberg, Germany
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Martin Beck,
Roles Conceptualization
Current address: Max Planck Institute of Biophysics, Frankfurt am Main, Germany
Affiliation Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
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Anne-Claude Gavin ,
Roles Conceptualization, Funding acquisition, Writing – original draft, Writing – review & editing
* E-mail: mkuhn@embl.de (MK); Anne-Claude.Gavin@unige.ch (A-CG); bork@embl.de (PB)
Current address: Department for Cell Physiology and Metabolism, University of Geneva, Centre Medical Universitaire, Geneva, Switzerland
Affiliation Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
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Peer Bork
Roles Conceptualization, Writing – original draft, Writing – review & editing
* E-mail: mkuhn@embl.de (MK); Anne-Claude.Gavin@unige.ch (A-CG); bork@embl.de (PB)
Affiliations Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany, Molecular Medicine Partnership Unit (MMPU), Heidelberg, Germany, Max Delbrück Center for Molecular Medicine, Berlin, Germany, Department of Bioinformatics, Biocenter, University of Würzburg, Würzburg, Germany
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Coupling proteomics and metabolomics for the unsupervised identification of protein–metabolite interactions in Chaetomium thermophilum
- Yuanyue Li,
- Michael Kuhn,
- Joanna Zukowska-Kasprzyk,
- Marco L. Hennrich,
- Panagiotis L. Kastritis,
- Francis J. O’Reilly,
- Prasad Phapale,
- Martin Beck,
- Anne-Claude Gavin,
- Peer Bork
![PLOS](/resource/img/logo-plos.png)
- Published: July 9, 2021
- https://doi.org/10.1371/journal.pone.0254429