The beneficial effect of chronic muscular exercise on muscle fragility is increased by Prox1 gene transfer in dystrophic mdx muscle

Alexandra Monceau; Clément Delacroix; Mégane Lemaitre; Gaelle Revet; Denis Furling; Onnik Agbulut; Arnaud Klein; Arnaud Ferry

doi:10.1371/journal.pone.0254274

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Open Access

Peer-reviewed

Research Article

The beneficial effect of chronic muscular exercise on muscle fragility is increased by Prox1 gene transfer in dystrophic mdx muscle

Alexandra Monceau,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Visualization

Affiliation Myology Center of Research, Association of Myology Institute, UMRS974, Inserm, Sorbonne Université, Paris, France
⨯
Clément Delacroix,

Roles Formal analysis, Investigation, Visualization

Affiliation Myology Center of Research, Association of Myology Institute, UMRS974, Inserm, Sorbonne Université, Paris, France
⨯
Mégane Lemaitre,

Roles Formal analysis, Investigation, Methodology

Affiliation UMS 28, Sorbonne Université, Paris, France
⨯
Gaelle Revet,

Roles Investigation, Visualization

Affiliation Biological Adaptation and Ageing, Institute of Paris-Seine Biology, UMR CNRS 8256, Inserm ERL U1164, Sorbonne Université, Paris, France
⨯
Denis Furling,

Roles Project administration, Resources, Supervision, Writing – review & editing

Affiliation Myology Center of Research, Association of Myology Institute, UMRS974, Inserm, Sorbonne Université, Paris, France
⨯
Onnik Agbulut,

Roles Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Writing – review & editing

Affiliation Biological Adaptation and Ageing, Institute of Paris-Seine Biology, UMR CNRS 8256, Inserm ERL U1164, Sorbonne Université, Paris, France
⨯
Arnaud Klein,

Roles Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

Affiliation Myology Center of Research, Association of Myology Institute, UMRS974, Inserm, Sorbonne Université, Paris, France
⨯
Arnaud Ferry

Roles Conceptualization, Formal analysis, Investigation, Project administration, Validation, Writing – original draft, Writing – review & editing

* E-mail: arnaud.ferry@upmc.fr

Affiliations Myology Center of Research, Association of Myology Institute, UMRS974, Inserm, Sorbonne Université, Paris, France, Université Paris Cité, Paris, France

https://orcid.org/0000-0002-6050-4556

⨯

The beneficial effect of chronic muscular exercise on muscle fragility is increased by Prox1 gene transfer in dystrophic mdx muscle

Alexandra Monceau,
Clément Delacroix,
Mégane Lemaitre,
Gaelle Revet,
Denis Furling,
Onnik Agbulut,
Arnaud Klein,
Arnaud Ferry

Published: April 18, 2022
https://doi.org/10.1371/journal.pone.0254274
See the preprint

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Muscle contraction
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Muscle proteins
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Sedentary behavior
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Gene expression
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Running
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