Synthetic modified Fezf2 mRNA (modRNA) with concurrent small molecule SIRT1 inhibition enhances refinement of cortical subcerebral/corticospinal neuron identity from mouse embryonic stem cells

• Cameron Sadegh,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Stem Cell and Regenerative Biology, Center for Brain Science, and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, United States of America, Department of Neurosurgery, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, United States of America

  https://orcid.org/0000-0003-2231-9015

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• Wataru Ebina,

  Roles Data curation, Investigation, Methodology, Writing – review & editing

  Affiliations Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, Massachusetts, United States of America, Division of Hematology/Oncology, Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Boston, Massachusetts, United States of America

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• Anthony C. Arvanites,

  Roles Conceptualization, Data curation, Formal analysis, Resources, Software, Supervision, Writing – review & editing

  Affiliation Department of Stem Cell and Regenerative Biology, and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, United States of America

  https://orcid.org/0000-0002-0988-8347

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• Lance S. Davidow,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources, Software, Writing – review & editing

  Affiliation Department of Stem Cell and Regenerative Biology, and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, United States of America

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• Lee L. Rubin,

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Writing – review & editing

  Affiliation Department of Stem Cell and Regenerative Biology, and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, United States of America

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• Jeffrey D. Macklis

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Software, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: jeffrey_macklis@harvard.edu

  Affiliation Department of Stem Cell and Regenerative Biology, Center for Brain Science, and Harvard Stem Cell Institute, Harvard University, Cambridge, Massachusetts, United States of America

  https://orcid.org/0000-0003-3662-9698

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