Next-generation sequencing of BRCA1 and BRCA2 genes in Moroccan prostate cancer patients with positive family history

Fatiha Salmi; Fatima Maachi; Amal Tazzite; Rachid Aboutaib; Jamal Fekkak; Houssine Azeddoug; Hassan Jouhadi

doi:10.1371/journal.pone.0254101

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Open Access

Peer-reviewed

Research Article

Next-generation sequencing of BRCA1 and BRCA2 genes in Moroccan prostate cancer patients with positive family history

Fatiha Salmi ,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: salmi_fatiha@hotmail.com

Affiliation Laboratory of Genetics and Molecular Pathology, Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Casablanca, Morocco

https://orcid.org/0000-0003-3472-830X

⨯
Fatima Maachi,

Roles Methodology, Validation

Affiliation Helicobacter Pylori and Gastric Pathologies Laboratory, Pasteur Institute of Morocco, Casablanca, Morocco
⨯
Amal Tazzite,

Roles Validation, Writing – review & editing

Affiliation Laboratory of Genetics and Molecular Pathology, Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Casablanca, Morocco
⨯
Rachid Aboutaib,

Roles Investigation, Validation

Affiliation Department of Urology, Ibn Rochd University Hospital Center, Casablanca, Morocco
⨯
Jamal Fekkak,

Roles Formal analysis, Methodology, Software, Validation

Affiliation Molecular Biology Department, Anoual Laboratory, Casablanca, Morocco
⨯
Houssine Azeddoug,

Roles Investigation, Validation

Affiliation Faculty of Sciences-Biochemistry and Molecular Biology Laboratory, University Hassan II Casablanca, Casablanca, Morocco
⨯
Hassan Jouhadi

Roles Conceptualization, Investigation, Project administration, Supervision, Validation, Writing – review & editing

Affiliations Laboratory of Genetics and Molecular Pathology, Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, Casablanca, Morocco, Mohammed VI Center for Cancer Treatment, Ibn Rochd University Hospital Center, Casablanca, Morocco
⨯

Next-generation sequencing of BRCA1 and BRCA2 genes in Moroccan prostate cancer patients with positive family history

Fatiha Salmi,
Fatima Maachi,
Amal Tazzite,
Rachid Aboutaib,
Jamal Fekkak,
Houssine Azeddoug,
Hassan Jouhadi

Published: July 9, 2021
https://doi.org/10.1371/journal.pone.0254101

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Genetic causes of cancer
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Prostate cancer
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Arabic people
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Introns
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Deletion mutation
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Insertion mutation
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Mutation detection
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Next-generation sequencing
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