Real-world outcomes of first- and second-generation tyrosine kinase inhibitors first-line in patients with epidermal growth factor receptor mutation-positive non-small cell lung cancer: A retrospective observational cohort study

Wei-Wei Ng; Chen-Chun Lin; Ching-Yuan Cheng; Jiunn-Song Jiang; Shang-Jyh Kao; Diana Yuwung Yeh

doi:10.1371/journal.pone.0253335

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Peer-reviewed

Research Article

Real-world outcomes of first- and second-generation tyrosine kinase inhibitors first-line in patients with epidermal growth factor receptor mutation-positive non-small cell lung cancer: A retrospective observational cohort study

Wei-Wei Ng,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Validation, Visualization, Writing – original draft

Affiliation Division of Chest Medicine, Department of Internal Medicine, Shin Kong Wu-Ho-Su Memorial Hospital, Taipei, Taiwan
⨯
Chen-Chun Lin,

Roles Resources

Affiliations Division of Chest Medicine, Department of Internal Medicine, Shin Kong Wu-Ho-Su Memorial Hospital, Taipei, Taiwan, School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan
⨯
Ching-Yuan Cheng,

Roles Validation

Affiliation Division of Chest Medicine, Department of Internal Medicine, Shin Kong Wu-Ho-Su Memorial Hospital, Taipei, Taiwan
⨯
Jiunn-Song Jiang,

Roles Resources

Affiliations Division of Chest Medicine, Department of Internal Medicine, Shin Kong Wu-Ho-Su Memorial Hospital, Taipei, Taiwan, School of Respiratory Therapy, Taipei Medical University, Taipei, Taiwan
⨯
Shang-Jyh Kao,

Roles Resources

Affiliations Division of Chest Medicine, Department of Internal Medicine, Shin Kong Wu-Ho-Su Memorial Hospital, Taipei, Taiwan, School of Respiratory Therapy, Taipei Medical University, Taipei, Taiwan
⨯
Diana Yuwung Yeh

Roles Conceptualization, Data curation, Resources, Supervision, Validation, Writing – review & editing

* E-mail: m004917@ms.skh.org.tw

Affiliations Division of Chest Medicine, Department of Internal Medicine, Shin Kong Wu-Ho-Su Memorial Hospital, Taipei, Taiwan, School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan
⨯

Real-world outcomes of first- and second-generation tyrosine kinase inhibitors first-line in patients with epidermal growth factor receptor mutation-positive non-small cell lung cancer: A retrospective observational cohort study

Wei-Wei Ng,
Chen-Chun Lin,
Ching-Yuan Cheng,
Jiunn-Song Jiang,
Shang-Jyh Kao,
Diana Yuwung Yeh

Published: June 24, 2021
https://doi.org/10.1371/journal.pone.0253335

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Cancers and neoplasms
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Deletion mutation
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Non-small cell lung cancer
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Tyrosine kinase inhibitors
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Cancer treatment
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Epidermal growth factor
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Lung and intrathoracic tumors
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