Single-cell RNAseq and longitudinal proteomic analysis of a novel semi-spontaneous urothelial cancer model reveals tumor cell heterogeneity and pretumoral urine protein alterations

• Iliana K. Kerzeli,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmaceutical Biosciences, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

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• Martin Lord,

  Roles Data curation, Formal analysis, Investigation, Software, Validation, Writing – review & editing

  Affiliation Department of Pharmaceutical Biosciences, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

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• Milena Doroszko,

  Roles Data curation, Formal analysis, Investigation, Methodology, Software, Supervision, Validation, Visualization, Writing – review & editing

  Affiliation Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

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• Ramy Elgendy,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

  https://orcid.org/0000-0002-2592-3448

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• Aikaterini Chourlia,

  Roles Formal analysis, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation Department of Pharmaceutical Biosciences, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

  ⨯
• Ivan Stepanek,

  Roles Data curation, Investigation, Methodology, Project administration, Writing – review & editing

  Affiliation Department of Pharmaceutical Biosciences, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

  ⨯
• Elinor Larsson,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Department of Pharmaceutical Biosciences, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

  ⨯
• Luuk van Hooren,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

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• Sven Nelander,

  Roles Funding acquisition, Methodology, Resources, Supervision, Writing – review & editing

  Affiliation Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

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• Per-Uno Malmstrom,

  Roles Funding acquisition, Supervision, Writing – review & editing

  Affiliation Department of Surgical Sciences, Uppsala University, Uppsala, Sweden

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• Anca Dragomir,

  Roles Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Validation, Visualization, Writing – review & editing

  Affiliation Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

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• Ulrika Segersten,

  Roles Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  Affiliation Department of Surgical Sciences, Uppsala University, Uppsala, Sweden

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• Sara M. Mangsbo

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: sara.mangsbo@farmbio.uu.se

  Affiliation Department of Pharmaceutical Biosciences, Science for Life Laboratory, Uppsala University, Uppsala, Sweden

  https://orcid.org/0000-0002-1355-2678

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