Disruption of the pro-inflammatory, anti-inflammatory cytokines and tight junction proteins expression, associated with changes of the composition of the gut microbiota in patients with irritable bowel syndrome

V. Ivashkin; Y. Poluektov; E. Kogan; O. Shifrin; A. Sheptulin; A. Kovaleva; A. Kurbatova; G. Krasnov; E. Poluektova

doi:10.1371/journal.pone.0252930

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Open Access

Peer-reviewed

Research Article

Disruption of the pro-inflammatory, anti-inflammatory cytokines and tight junction proteins expression, associated with changes of the composition of the gut microbiota in patients with irritable bowel syndrome

V. Ivashkin,

Roles Conceptualization, Project administration, Supervision

Affiliation I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
⨯
Y. Poluektov ,

Roles Data curation, Investigation, Writing – review & editing

* E-mail: yuripoul@gmail.com

Affiliation Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia

https://orcid.org/0000-0002-9710-7490

⨯
E. Kogan,

Roles Investigation, Methodology, Software

Affiliation I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
⨯
O. Shifrin,

Roles Data curation, Methodology

Affiliation I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
⨯
A. Sheptulin,

Roles Data curation, Investigation

Affiliation I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
⨯
A. Kovaleva,

Roles Formal analysis, Investigation, Writing – original draft

Affiliation I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
⨯
A. Kurbatova,

Roles Investigation, Methodology

Affiliation I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation

https://orcid.org/0000-0002-6154-8163

⨯
G. Krasnov,

Roles Methodology, Software

Affiliation Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia
⨯
E. Poluektova

Roles Data curation, Investigation, Project administration, Writing – review & editing

Affiliation I.M. Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russian Federation
⨯

Disruption of the pro-inflammatory, anti-inflammatory cytokines and tight junction proteins expression, associated with changes of the composition of the gut microbiota in patients with irritable bowel syndrome

V. Ivashkin,
Y. Poluektov,
E. Kogan,
O. Shifrin,
A. Sheptulin,
A. Kovaleva,
A. Kurbatova,
G. Krasnov,
E. Poluektova

Published: June 11, 2021
https://doi.org/10.1371/journal.pone.0252930

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Gastrointestinal tract
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Biopsy
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Cytokines
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