A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel disease

Maegan L. Capitano; Aruna Jaiswal; Hal E. Broxmeyer; Yilianys Pride; Sarah Glover; Fatemah G. Amlashi; Austin Kirby; Gayathri Srinivasan; Elizabeth A. Williamson; Daniel Mais; Robert Hromas

doi:10.1371/journal.pone.0252805

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Open Access

Peer-reviewed

Research Article

A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel disease

Maegan L. Capitano,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, United States of America
⨯
Aruna Jaiswal,

Roles Investigation, Methodology, Writing – review & editing

Affiliation Department of Medicine and the Mays Cancer Center, University of Texas School Health Science Center at San Antonio, San Antonio, TX, United States of America
⨯
Hal E. Broxmeyer,

Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

Affiliation Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, United States of America
⨯
Yilianys Pride,

Roles Conceptualization, Data curation, Resources

Affiliation Division of Gastroenterology, Department of Medicine, University of Mississippi Medical Center, Jackson, MI, United States of America
⨯
Sarah Glover,

Roles Conceptualization, Data curation, Formal analysis, Writing – review & editing

Affiliation Division of Gastroenterology, Department of Medicine, University of Mississippi Medical Center, Jackson, MI, United States of America
⨯
Fatemah G. Amlashi,

Roles Data curation, Investigation, Methodology

Affiliation Department of Pathology, University of Texas School Health Science Center at San Antonio, San Antonio, TX, United States of America
⨯
Austin Kirby,

Roles Investigation, Methodology

Affiliation Department of Medicine and the Mays Cancer Center, University of Texas School Health Science Center at San Antonio, San Antonio, TX, United States of America
⨯
Gayathri Srinivasan,

Roles Conceptualization, Investigation, Methodology

Affiliation Department of Medicine and the Mays Cancer Center, University of Texas School Health Science Center at San Antonio, San Antonio, TX, United States of America
⨯
Elizabeth A. Williamson,

Roles Conceptualization, Methodology

Affiliation Department of Medicine and the Mays Cancer Center, University of Texas School Health Science Center at San Antonio, San Antonio, TX, United States of America
⨯
Daniel Mais,

Roles Data curation, Formal analysis, Methodology, Resources

Affiliation Department of Pathology, University of Texas School Health Science Center at San Antonio, San Antonio, TX, United States of America
⨯
Robert Hromas

Roles Conceptualization, Data curation, Formal analysis, Visualization, Writing – original draft

* E-mail: hromas@uthscsa.edu

Affiliation Department of Medicine and the Mays Cancer Center, University of Texas School Health Science Center at San Antonio, San Antonio, TX, United States of America

https://orcid.org/0000-0002-1916-6276

⨯

A humanized monoclonal antibody against the endothelial chemokine CCL21 for the diagnosis and treatment of inflammatory bowel disease

Maegan L. Capitano,
Aruna Jaiswal,
Hal E. Broxmeyer,
Yilianys Pride,
Sarah Glover,
Fatemah G. Amlashi,
Austin Kirby,
Gayathri Srinivasan,
Elizabeth A. Williamson,
Daniel Mais

Published: July 1, 2021
https://doi.org/10.1371/journal.pone.0252805

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