Inhibition of PI3K and MAPK pathways along with KIT inhibitors as a strategy to overcome drug resistance in gastrointestinal stromal tumors

• Anu Gupta,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Project administration, Validation, Writing – original draft

  Affiliation Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America

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• Shuang Ma,

  Roles Investigation

  Affiliation Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America

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• Kepeng Che,

  Roles Investigation

  Affiliation Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America

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• Ajaybabu V. Pobbati,

  Roles Writing – review & editing

  Affiliation Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America

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• Brian P. Rubin

  Roles Conceptualization, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – review & editing

  * E-mail: rubinb2@ccf.org

  Affiliations Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America, Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America

  https://orcid.org/0000-0002-0657-3024

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