Heparan sulfate proteoglycans in beta cells provide a critical link between endoplasmic reticulum stress, oxidative stress and type 2 diabetes

• Sarita Dhounchak,

  Roles Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia

  ⨯
• Sarah K. Popp,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia

  ⨯
• Debra J. Brown,

  Roles Investigation, Methodology

  Affiliation Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia

  ⨯
• D. Ross Laybutt,

  Roles Resources, Writing – review & editing

  Affiliation Garvan Institute of Medical Research, St Vincent’s Clinical School, The University of NSW (UNSW), Sydney, New South Wales, Australia

  ⨯
• Trevor J. Biden,

  Roles Resources, Writing – review & editing

  Affiliation Garvan Institute of Medical Research, St Vincent’s Clinical School, The University of NSW (UNSW), Sydney, New South Wales, Australia

  ⨯
• Stefan R. Bornstein,

  Roles Funding acquisition, Writing – review & editing

  Affiliation Department of Internal Medicine III, Carl Gustav Carus Medical School, Technical University of Dresden, Dresden, Germany

  ⨯
• Christopher R. Parish,

  Roles Conceptualization, Writing – review & editing

  Affiliation ACRF Department of Cancer Biology and Therapeutics, The John Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia

  ⨯
• Charmaine J. Simeonovic

  Roles Conceptualization, Funding acquisition, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: Charmaine.Simeonovic@anu.edu.au

  Affiliation Department of Immunology and Infectious Disease, The John Curtin School of Medical Research, The Australian National University, Canberra, Australian Capital Territory, Australia

  https://orcid.org/0000-0002-7161-5825

  ⨯