HeLa TI cell-based assay as a new approach to screen for chemicals able to reactivate the expression of epigenetically silenced genes

• Varvara Maksimova ,

  Roles Formal analysis, Investigation, Visualization, Writing – original draft

  * E-mail: lavarvar@gmail.com

  Affiliation Department of Chemical Carcinogenesis, Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia

  https://orcid.org/0000-0003-0896-2952

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• Natalya Shalginskikh,

  Roles Investigation, Methodology

  Affiliations Department of Chemical Carcinogenesis, Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia, Fox Chase Cancer Center, Temple University, Philadelphia, PA, United States of America

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• Olga Vlasova,

  Roles Formal analysis, Visualization

  Affiliation Department of Chemical Carcinogenesis, Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia

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• Olga Usalka,

  Roles Formal analysis, Investigation, Methodology

  Affiliations Department of Chemical Carcinogenesis, Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia, International School "Medicine of the Future", Sechenov University, Moscow, Russia

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• Anastasia Beizer,

  Roles Investigation, Methodology

  Affiliation Department of Chemical Carcinogenesis, Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia

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• Polina Bugaeva,

  Roles Investigation, Visualization

  Affiliation Department of Translational Neurobiology, Julius-Maximilians-Universität of Würzburg, Würzburg, Germany

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• Dmitry Fedorov,

  Roles Investigation

  Affiliations Department of Chemical Carcinogenesis, Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia, Department of Urology, A.V. Vishnevsky National Medical Research Center of Surgery, Moscow, Russia

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• Olga Lizogub,

  Roles Investigation

  Affiliations Department of Chemical Carcinogenesis, Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia, International School "Medicine of the Future", Sechenov University, Moscow, Russia

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• Ekaterina Lesovaya,

  Roles Formal analysis, Methodology

  Affiliations Department of Chemical Carcinogenesis, Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia, Department of Oncology, Ryazan State Medical University, Ryazan, Russia

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• Richard Katz,

  Roles Writing – review & editing

  Affiliation Fox Chase Cancer Center, Temple University, Philadelphia, PA, United States of America

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• Gennady Belitsky,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Chemical Carcinogenesis, Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia

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• Kirill Kirsanov,

  Roles Conceptualization, Funding acquisition, Project administration, Writing – review & editing

  Affiliations Department of Chemical Carcinogenesis, Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia, Department of General and Medical Practice, Medical Institute, The Peoples’ Friendship University of Russia, Moscow, Russia

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• Marianna Yakubovskaya

  Roles Conceptualization, Formal analysis, Methodology, Project administration, Supervision, Writing – review & editing

  Affiliation Department of Chemical Carcinogenesis, Institute of Carcinogenesis, N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia

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