Differences in levels of phosphatidylinositols in healthy and stable Coronary Artery Disease subjects revealed by HILIC-MRM method with SERRF normalization

Yue Huang; Ruipeng Mu; David Wen; Joseph S. Grimsby; Meina Liang; Anton I. Rosenbaum

doi:10.1371/journal.pone.0252426

Loading metrics

Open Access

Peer-reviewed

Research Article

Differences in levels of phosphatidylinositols in healthy and stable Coronary Artery Disease subjects revealed by HILIC-MRM method with SERRF normalization

Yue Huang,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Writing – original draft, Writing – review & editing

Affiliation Integrated Bioanalysis, Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, South San Francisco, CA, United States of America

https://orcid.org/0000-0003-2788-0856

⨯
Ruipeng Mu,

Roles Data curation, Formal analysis, Methodology, Writing – review & editing

Affiliation Integrated Bioanalysis, Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, South San Francisco, CA, United States of America
⨯
David Wen,

Roles Formal analysis, Software, Visualization, Writing – review & editing

Affiliation Integrated Bioanalysis, Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, South San Francisco, CA, United States of America
⨯
Joseph S. Grimsby,

Roles Conceptualization, Writing – review & editing

Affiliation Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, United States of America

https://orcid.org/0000-0002-0388-1427

⨯
Meina Liang,

Roles Supervision, Writing – review & editing

Affiliation Integrated Bioanalysis, Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, South San Francisco, CA, United States of America
⨯
Anton I. Rosenbaum

Roles Conceptualization, Formal analysis, Methodology, Software, Supervision, Writing – original draft, Writing – review & editing

* E-mail: anton.rosenbaum@astrazeneca.com

Affiliation Integrated Bioanalysis, Clinical Pharmacology and Quantitative Pharmacology, Clinical Pharmacology & Safety Sciences, R&D, AstraZeneca, South San Francisco, CA, United States of America

https://orcid.org/0000-0003-1939-951X

⨯

Differences in levels of phosphatidylinositols in healthy and stable Coronary Artery Disease subjects revealed by HILIC-MRM method with SERRF normalization

Yue Huang,
Ruipeng Mu,
David Wen,
Joseph S. Grimsby,
Meina Liang,
Anton I. Rosenbaum

Published: June 4, 2021
https://doi.org/10.1371/journal.pone.0252426

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Lipids
Is the Subject Area "Lipids" applicable to this article?

Thanks for your feedback.
Biomarkers
Is the Subject Area "Biomarkers" applicable to this article?

Thanks for your feedback.
Lipid analysis
Is the Subject Area "Lipid analysis" applicable to this article?

Thanks for your feedback.
Automation
Is the Subject Area "Automation" applicable to this article?

Thanks for your feedback.
Chromatographic techniques
Is the Subject Area "Chromatographic techniques" applicable to this article?

Thanks for your feedback.
Algorithms
Is the Subject Area "Algorithms" applicable to this article?

Thanks for your feedback.
Phospholipids
Is the Subject Area "Phospholipids" applicable to this article?

Thanks for your feedback.
Lipid profiles
Is the Subject Area "Lipid profiles" applicable to this article?

Thanks for your feedback.