Sprouty4 negatively regulates ERK/MAPK signaling and the transition from in situ to invasive breast ductal carcinoma

Ethan J. Brock; Ryan M. Jackson; Julie L. Boerner; Quanwen Li; Meredith A. Tennis; Bonnie F. Sloane; Raymond R. Mattingly

doi:10.1371/journal.pone.0252314

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Open Access

Peer-reviewed

Research Article

Sprouty4 negatively regulates ERK/MAPK signaling and the transition from in situ to invasive breast ductal carcinoma

Ethan J. Brock,

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

Affiliation Department of Oncology, Wayne State University School of Medicine, Detroit, MI, United states of America

https://orcid.org/0000-0002-6502-851X

⨯
Ryan M. Jackson,

Roles Investigation

Affiliation Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI, United states of America
⨯
Julie L. Boerner,

Roles Conceptualization, Formal analysis, Investigation, Writing – review & editing

Affiliation Department of Oncology, Wayne State University School of Medicine, Detroit, MI, United states of America
⨯
Quanwen Li,

Roles Conceptualization, Resources

Affiliation Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI, United states of America
⨯
Meredith A. Tennis,

Roles Resources, Writing – review & editing

Affiliation Division of Pulmonary Sciences and Critical Care Medicine, Department of Medicine, University of Colorado Denver Anschutz Medical Campus, Aurora, CO, United states of America
⨯
Bonnie F. Sloane,

Roles Conceptualization, Funding acquisition, Methodology, Writing – review & editing

Affiliations Department of Oncology, Wayne State University School of Medicine, Detroit, MI, United states of America, Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI, United states of America
⨯
Raymond R. Mattingly

Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – review & editing

* E-mail: r.mattingly@wayne.edu

Affiliations Department of Oncology, Wayne State University School of Medicine, Detroit, MI, United states of America, Department of Pharmacology, Wayne State University School of Medicine, Detroit, MI, United states of America
⨯

Sprouty4 negatively regulates ERK/MAPK signaling and the transition from in situ to invasive breast ductal carcinoma

Ethan J. Brock,
Ryan M. Jackson,
Julie L. Boerner,
Quanwen Li,
Meredith A. Tennis,
Bonnie F. Sloane,
Raymond R. Mattingly

Published: May 28, 2021
https://doi.org/10.1371/journal.pone.0252314

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