Phlpp1 is induced by estrogen in osteoclasts and its loss in Ctsk-expressing cells does not protect against ovariectomy-induced bone loss

• Marcelline K. Hanson ,

  Contributed equally to this work with: Marcelline K. Hanson, Ismael Y. Karkache

  Roles Data curation, Formal analysis, Investigation, Writing – original draft, Writing – review & editing

  Affiliation Department of Orthopedic Surgery, University of Minnesota, Minneapolis, MN, United States of America

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• Ismael Y. Karkache ,

  Contributed equally to this work with: Marcelline K. Hanson, Ismael Y. Karkache

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Orthopedic Surgery, University of Minnesota, Minneapolis, MN, United States of America

  ⨯
• David H. H. Molstad,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Orthopedic Surgery, University of Minnesota, Minneapolis, MN, United States of America

  ⨯
• Andrew A. Norton,

  Roles Data curation, Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Developmental and Surgical Sciences, University of Minnesota, Minneapolis, MN, United States of America

  ⨯
• Kim C. Mansky,

  Roles Investigation, Supervision, Writing – review & editing

  Affiliation Department of Developmental and Surgical Sciences, University of Minnesota, Minneapolis, MN, United States of America

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• Elizabeth W. Bradley

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ebradle1@umn.edu

  Affiliations Department of Orthopedic Surgery, University of Minnesota, Minneapolis, MN, United States of America, Stem Cell Institute, University of Minnesota, Minneapolis, MN, United States of America

  https://orcid.org/0000-0002-8814-5524

  ⨯