Correlation among isolated teratozoospermia, sperm DNA fragmentation and markers of systemic inflammation in primary infertile men

Luigi Candela; Luca Boeri; Paolo Capogrosso; Walter Cazzaniga; Edoardo Pozzi; Federico Belladelli; Andrea Baudo; Andrea Ravizzoli; Eugenio Ventimiglia; Paola Viganò; Massimo Alfano; Costantino Abbate; Julian Cornelius; Agostino Mattei; Francesco Montorsi; Andrea Salonia

doi:10.1371/journal.pone.0251608

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Peer-reviewed

Research Article

Correlation among isolated teratozoospermia, sperm DNA fragmentation and markers of systemic inflammation in primary infertile men

Luigi Candela ,

Contributed equally to this work with: Luigi Candela, Luca Boeri

Roles Conceptualization, Data curation, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliations Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy, University Vita-Salute San Raffaele, Milan, Italy
⨯
Luca Boeri ,

Contributed equally to this work with: Luigi Candela, Luca Boeri

Roles Conceptualization, Data curation, Formal analysis, Methodology, Supervision, Validation, Writing – original draft, Writing – review & editing

Affiliations Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy, Department of Urology, Foundation IRCCS Ca’ Granda–Ospedale Maggiore Policlinico, University of Milan, Milan, Italy
⨯
Paolo Capogrosso,

Roles Formal analysis, Supervision, Validation, Writing – review & editing

Affiliations Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy, Department of Urology and Andrology, Ospedale di Circolo and Macchi Foundation,Varese, Italy
⨯
Walter Cazzaniga,

Roles Conceptualization, Data curation, Formal analysis, Methodology, Validation, Writing – original draft, Writing – review & editing

Affiliations Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy, University Vita-Salute San Raffaele, Milan, Italy
⨯
Edoardo Pozzi,

Roles Data curation, Writing – review & editing

Affiliations Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy, University Vita-Salute San Raffaele, Milan, Italy
⨯
Federico Belladelli,

Roles Data curation, Writing – review & editing

Affiliations Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy, University Vita-Salute San Raffaele, Milan, Italy
⨯
Andrea Baudo,

Roles Data curation, Writing – review & editing

Affiliations Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy, University Vita-Salute San Raffaele, Milan, Italy
⨯
Andrea Ravizzoli,

Roles Data curation, Writing – review & editing

Affiliations Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy, University Vita-Salute San Raffaele, Milan, Italy
⨯
Eugenio Ventimiglia,

Roles Data curation, Formal analysis, Writing – review & editing

Affiliation Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy
⨯
Paola Viganò,

Roles Supervision, Validation, Writing – review & editing

Affiliations Obstetrics and Gynaecology Department, IRCCS Ospedale San Raffaele, Milan, Italy, Division of Genetics and Cell Biology, Reproductive Sciences Laboratory, IRCCS Ospedale San Raffaele, Milan, Italy
⨯
Massimo Alfano,

Roles Supervision, Writing – review & editing

Affiliation Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy
⨯
Costantino Abbate,

Roles Data curation, Writing – review & editing

Affiliation Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy
⨯
Julian Cornelius,

Roles Writing – review & editing

Affiliation Department of Urology, Luzerner Kantonsspital, Lucerne, Switzerland
⨯
Agostino Mattei,

Roles Writing – review & editing

Affiliation Department of Urology, Luzerner Kantonsspital, Lucerne, Switzerland
⨯
Francesco Montorsi,

Roles Supervision, Writing – review & editing

Affiliations Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy, University Vita-Salute San Raffaele, Milan, Italy
⨯
[ ... ],
Andrea Salonia

Roles Conceptualization, Formal analysis, Methodology, Supervision, Validation, Writing – review & editing

* E-mail: salonia.andrea@hsr.it

Affiliations Division of Experimental Oncology/Unit of Urology, URI, IRCCS Ospedale San Raffaele, Milan, Italy, University Vita-Salute San Raffaele, Milan, Italy

https://orcid.org/0000-0002-0595-7165

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Correlation among isolated teratozoospermia, sperm DNA fragmentation and markers of systemic inflammation in primary infertile men

Luigi Candela,
Luca Boeri,
Paolo Capogrosso,
Walter Cazzaniga,
Edoardo Pozzi,
Federico Belladelli,
Andrea Baudo,
Andrea Ravizzoli,
Eugenio Ventimiglia,
Paola Viganò

Published: June 7, 2021
https://doi.org/10.1371/journal.pone.0251608

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