Evaluation of a connectivity-based imaging metric that reflects functional decline in Multiple Sclerosis

Katherine A. Koenig; Erik B. Beall; Ken E. Sakaie; Daniel Ontaneda; Lael Stone; Stephen M. Rao; Kunio Nakamura; Stephen E. Jones; Mark J. Lowe

doi:10.1371/journal.pone.0251338

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Open Access

Peer-reviewed

Research Article

Evaluation of a connectivity-based imaging metric that reflects functional decline in Multiple Sclerosis

Katherine A. Koenig ,

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

* E-mail: koenigk@ccf.org

Affiliation Imaging Sciences, Imaging Institute, Cleveland Clinic, Cleveland, OH, United States of America

https://orcid.org/0000-0002-1504-7130

⨯
Erik B. Beall,

Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – original draft

Affiliation Imaging Sciences, Imaging Institute, Cleveland Clinic, Cleveland, OH, United States of America
⨯
Ken E. Sakaie,

Roles Formal analysis, Methodology, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliation Imaging Sciences, Imaging Institute, Cleveland Clinic, Cleveland, OH, United States of America
⨯
Daniel Ontaneda,

Roles Investigation, Resources, Writing – review & editing

Affiliation Mellen Center, Neurologic Institute, Cleveland Clinic, Cleveland, OH, United States of America
⨯
Lael Stone,

Roles Investigation, Resources

Affiliation Mellen Center, Neurologic Institute, Cleveland Clinic, Cleveland, OH, United States of America
⨯
Stephen M. Rao,

Roles Data curation, Investigation, Methodology

Affiliation Schey Center for Cognitive Neuroimaging, Neurologic Institute, Cleveland Clinic, Cleveland, OH, United States of America
⨯
Kunio Nakamura,

Roles Data curation, Formal analysis, Methodology, Software

Affiliation Lerner Research Institute, Cleveland Clinic, Cleveland, OH, United States of America

https://orcid.org/0000-0002-7833-8138

⨯
Stephen E. Jones,

Roles Investigation

Affiliation Imaging Sciences, Imaging Institute, Cleveland Clinic, Cleveland, OH, United States of America
⨯
Mark J. Lowe

Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

Affiliation Imaging Sciences, Imaging Institute, Cleveland Clinic, Cleveland, OH, United States of America
⨯

Evaluation of a connectivity-based imaging metric that reflects functional decline in Multiple Sclerosis

Katherine A. Koenig,
Erik B. Beall,
Ken E. Sakaie,
Daniel Ontaneda,
Lael Stone,
Stephen M. Rao,
Kunio Nakamura,
Stephen E. Jones,
Mark J. Lowe

Published: June 8, 2021
https://doi.org/10.1371/journal.pone.0251338

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Multiple sclerosis
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Resting state functional magnetic resonance imaging
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Magnetic resonance imaging
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Left hemisphere
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