A systematic approach to the scale separation problem in the development of multiscale models

• Pinaki Bhattacharya ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  * E-mail: p.bhattacharya@sheffield.ac.uk

  Affiliations Department of Mechanical Engineering, University of Sheffield, Sheffield, United Kingdom, INSIGNEO Institute for in silico Medicine, University of Sheffield, Sheffield, United Kingdom

  https://orcid.org/0000-0003-1109-1174

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• Qiao Li,

  Roles Formal analysis, Investigation

  Affiliations Department of Mechanical Engineering, University of Sheffield, Sheffield, United Kingdom, INSIGNEO Institute for in silico Medicine, University of Sheffield, Sheffield, United Kingdom

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• Damien Lacroix,

  Roles Methodology, Writing – review & editing

  Affiliations Department of Mechanical Engineering, University of Sheffield, Sheffield, United Kingdom, INSIGNEO Institute for in silico Medicine, University of Sheffield, Sheffield, United Kingdom

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• Visakan Kadirkamanathan,

  Roles Methodology, Writing – review & editing

  Affiliations INSIGNEO Institute for in silico Medicine, University of Sheffield, Sheffield, United Kingdom, Department of Automatic Control and Systems Engineering, University of Sheffield, Sheffield, United Kingdom

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• Marco Viceconti

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Dipartimento di Ingegneria Industriale, Alma Mater Studiorum – University of Bologna, Bologna, Italy, Laboratorio di Tecnologia Medica, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy

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