Validation of protein arginine methyltransferase 5 (PRMT5) as a candidate therapeutic target in the spontaneous canine model of non-Hodgkin lymphoma

• Shelby L. Sloan ,

  Contributed equally to this work with: Shelby L. Sloan, Kyle A. Renaldo

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America, Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America

  https://orcid.org/0000-0001-7366-9184

  ⨯
• Kyle A. Renaldo ,

  Contributed equally to this work with: Shelby L. Sloan, Kyle A. Renaldo

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft

  Affiliation Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, United States of America

  ⨯
• Mackenzie Long,

  Roles Visualization

  Affiliations Department of Veterinary Biosciences, College of Veterinary Medicine, The Ohio State University, Columbus, Ohio, United States of America, Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America

  ⨯
• Ji-Hyun Chung,

  Roles Investigation, Validation, Visualization

  Affiliation Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America

  ⨯
• Lindsay E. Courtney,

  Roles Investigation

  Affiliation Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, United States of America

  ⨯
• Konstantin Shilo,

  Roles Data curation, Resources

  Affiliation Department of Pathology, The Ohio State University, Columbus, Ohio, United States of America

  https://orcid.org/0000-0002-6702-3130

  ⨯
• Youssef Youssef,

  Roles Investigation

  Affiliation Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America

  ⨯
• Sarah Schlotter,

  Roles Investigation

  Affiliation Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America

  ⨯
• Fiona Brown,

  Roles Visualization

  Affiliation Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America

  ⨯
• Brett G. Klamer,

  Roles Formal analysis

  Affiliation Department of Biomedical Informatics, Center for Biostatistics, The Ohio State University, Columbus, Ohio, United States of America

  ⨯
• Xiaoli Zhang,

  Roles Formal analysis

  Affiliation Department of Biomedical Informatics, Center for Biostatistics, The Ohio State University, Columbus, Ohio, United States of America

  ⨯
• Ayse S. Yilmaz,

  Roles Formal analysis

  Affiliation Department of Biomedical Informatics, Center for Biostatistics, The Ohio State University, Columbus, Ohio, United States of America

  ⨯
• Hatice G. Ozer,

  Roles Formal analysis

  Affiliation Department of Biomedical Informatics, Center for Biostatistics, The Ohio State University, Columbus, Ohio, United States of America

  ⨯
• Victor E. Valli †,

  † Deceased.

  Roles Resources

  Affiliation VDx Veterinary Diagnostics, Davis, California, United States of America

  ⨯
• Kris Vaddi,

  Roles Resources

  Affiliation Prelude Therapeutics, Wilmington, Delaware, United States of America

  ⨯
• Peggy Scherle,

  Roles Resources

  Affiliation Prelude Therapeutics, Wilmington, Delaware, United States of America

  ⨯
• Lapo Alinari,

  Roles Writing – review & editing

  Affiliation Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America

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• William C. Kisseberth ,

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: Kisseberth.2@osu.edu (WCK); Robert.Baiocchi@osumc.edu (RAB)

  ¶‡ These authors also contributed equally to this work

  Affiliations Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America, Department of Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, United States of America

  ⨯
•  [ ... ],
• Robert A. Baiocchi

  Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

  * E-mail: Kisseberth.2@osu.edu (WCK); Robert.Baiocchi@osumc.edu (RAB)

  ¶‡ These authors also contributed equally to this work

  Affiliation Division of Hematology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, United States of America

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