A novel preparative method for nanoparticle albumin-bound paclitaxel with high drug loading and its evaluation both in vitro and in vivo

• Yue Gao ,

  Contributed equally to this work with: Yue Gao, Jingxue Nai, Zhenbo Yang

  Roles Investigation, Methodology

  Affiliations Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China

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• Jingxue Nai ,

  Contributed equally to this work with: Yue Gao, Jingxue Nai, Zhenbo Yang

  Roles Data curation, Formal analysis, Investigation, Methodology

  Affiliations Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China, Wuhan University School of Pharmaceutical Sciences, Wuhan, China

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• Zhenbo Yang ,

  Contributed equally to this work with: Yue Gao, Jingxue Nai, Zhenbo Yang

  Roles Conceptualization, Investigation, Methodology

  Affiliation Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China

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• Jinbang Zhang,

  Roles Data curation, Formal analysis, Software

  Affiliations Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China, Pharmaceutical College of Henan University, Kaifeng, China

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• Siyu Ma,

  Roles Investigation, Methodology

  Affiliation Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China

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• Yumei Zhao,

  Roles Methodology

  Affiliation Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China

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• Hui Li,

  Roles Data curation, Formal analysis

  Affiliation Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China

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• Jiaxin Li,

  Roles Data curation, Formal analysis

  Affiliation Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China

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• Yang Yang,

  Roles Writing – review & editing

  Affiliation Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China

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• Meiyan Yang,

  Roles Writing – review & editing

  Affiliation Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China

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• Yuli Wang,

  Roles Writing – review & editing

  Affiliation Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China

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• Wei Gong,

  Roles Conceptualization, Writing – review & editing

  Affiliation Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China

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• Fanglin Yu,

  Roles Writing – review & editing

  Affiliation Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China

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• Chunsheng Gao ,

  Roles Conceptualization, Writing – review & editing

  * E-mail: dearwood2010@126.com (ZL); largedna@163.com (CG)

  Affiliations Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China, Pharmaceutical College of Henan University, Kaifeng, China

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• Zhiping Li ,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft

  * E-mail: dearwood2010@126.com (ZL); largedna@163.com (CG)

  Affiliation Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China

  https://orcid.org/0000-0003-1975-8447

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•  [ ... ],
• Xingguo Mei

  Roles Writing – review & editing

  Affiliation Department of Pharmaceutics, State key Laboratory of Toxicology and Medical Countermeasure, Beijing Institute of Pharmacology and Toxicology, Beijing, China

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