Up-regulation of cytosolic prostaglandin E synthase in fetal-membrane and amniotic prostaglandin E2 accumulation in labor

Nanase Takahashi; Toshiaki Okuno; Hiroki Fujii; Shintaro Makino; Masaya Takahashi; Mai Ohba; Kazuko Saeki; Atsuo Itakura; Satoru Takeda; Takehiko Yokomizo

doi:10.1371/journal.pone.0250638

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Open Access

Peer-reviewed

Research Article

Up-regulation of cytosolic prostaglandin E synthase in fetal-membrane and amniotic prostaglandin E₂ accumulation in labor

Nanase Takahashi,

Roles Conceptualization, Investigation, Writing – original draft, Writing – review & editing

Affiliations Department of Biochemistry, Juntendo University School of Medicine, Tokyo, Japan, Department of Obstetrics & Gynecology, Juntendo University School of Medicine, Tokyo, Japan
⨯
Toshiaki Okuno ,

Roles Conceptualization, Project administration, Writing – original draft, Writing – review & editing

* E-mail: tokuno@juntendo.ac.jp

Affiliation Department of Biochemistry, Juntendo University School of Medicine, Tokyo, Japan

https://orcid.org/0000-0003-0270-5744

⨯
Hiroki Fujii,

Roles Investigation

Affiliation Department of Biochemistry, Juntendo University School of Medicine, Tokyo, Japan
⨯
Shintaro Makino,

Roles Conceptualization, Resources, Validation

Affiliation Department of Obstetrics & Gynecology, Juntendo University Urayasu Hospital, Chiba, Japan
⨯
Masaya Takahashi,

Roles Investigation, Resources

Affiliation Department of Obstetrics & Gynecology, Juntendo University Urayasu Hospital, Chiba, Japan
⨯
Mai Ohba,

Roles Investigation, Methodology

Affiliation Department of Biochemistry, Juntendo University School of Medicine, Tokyo, Japan
⨯
Kazuko Saeki,

Roles Funding acquisition, Resources

Affiliation Department of Biochemistry, Juntendo University School of Medicine, Tokyo, Japan
⨯
Atsuo Itakura,

Roles Supervision

Affiliation Department of Obstetrics & Gynecology, Juntendo University School of Medicine, Tokyo, Japan
⨯
Satoru Takeda,

Roles Supervision

Affiliation Department of Obstetrics & Gynecology, Juntendo University School of Medicine, Tokyo, Japan
⨯
Takehiko Yokomizo

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

Affiliation Department of Biochemistry, Juntendo University School of Medicine, Tokyo, Japan

https://orcid.org/0000-0002-5219-1553

⨯

Up-regulation of cytosolic prostaglandin E synthase in fetal-membrane and amniotic prostaglandin E₂ accumulation in labor

Nanase Takahashi,
Toshiaki Okuno,
Hiroki Fujii,
Shintaro Makino,
Masaya Takahashi,
Mai Ohba,
Kazuko Saeki,
Atsuo Itakura,
Satoru Takeda,
Takehiko Yokomizo

Published: April 23, 2021
https://doi.org/10.1371/journal.pone.0250638

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