NMR analysis of the correlation of metabolic changes in blood and cerebrospinal fluid in Alzheimer model male and female mice

Filip Stojanovic; Mariam Taktek; Nam Huan Khieu; Junzhou Huang; Susan Jiang; Kerry Rennie; Balu Chakravarthy; Will J. Costain; Miroslava Cuperlovic-Culf

doi:10.1371/journal.pone.0250568

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Open Access

Peer-reviewed

Research Article

NMR analysis of the correlation of metabolic changes in blood and cerebrospinal fluid in Alzheimer model male and female mice

Filip Stojanovic,

Roles Investigation, Software, Writing – review & editing

Affiliation National Research Council of Canada, Digital Technologies Research Centre, Ottawa, Canada
⨯
Mariam Taktek,

Roles Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliation National Research Council of Canada, Digital Technologies Research Centre, Ottawa, Canada
⨯
Nam Huan Khieu,

Roles Formal analysis, Investigation, Writing – review & editing

Affiliation National Research Council of Canada, Human Health Therapeutics Research Centre, Ottawa, Canada
⨯
Junzhou Huang,

Roles Formal analysis, Investigation, Methodology, Writing – review & editing

Affiliation National Research Council of Canada, Human Health Therapeutics Research Centre, Ottawa, Canada
⨯
Susan Jiang,

Roles Investigation, Methodology, Writing – review & editing

Affiliation National Research Council of Canada, Human Health Therapeutics Research Centre, Ottawa, Canada
⨯
Kerry Rennie,

Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

Affiliation National Research Council of Canada, Human Health Therapeutics Research Centre, Ottawa, Canada
⨯
Balu Chakravarthy,

Roles Conceptualization, Resources, Supervision, Writing – review & editing

Affiliation National Research Council of Canada, Human Health Therapeutics Research Centre, Ottawa, Canada
⨯
Will J. Costain,

Roles Conceptualization, Methodology, Project administration, Resources, Writing – review & editing

Affiliation National Research Council of Canada, Human Health Therapeutics Research Centre, Ottawa, Canada

https://orcid.org/0000-0002-7476-6450

⨯
Miroslava Cuperlovic-Culf

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: miroslava.cuperlovic-culf@nrc-cnrc.gc.ca

Affiliation National Research Council of Canada, Digital Technologies Research Centre, Ottawa, Canada

https://orcid.org/0000-0002-9483-8159

⨯

NMR analysis of the correlation of metabolic changes in blood and cerebrospinal fluid in Alzheimer model male and female mice

Filip Stojanovic,
Mariam Taktek,
Nam Huan Khieu,
Junzhou Huang,
Susan Jiang,
Kerry Rennie,
Balu Chakravarthy,
Will J. Costain,
Miroslava Cuperlovic-Culf

Published: May 10, 2021
https://doi.org/10.1371/journal.pone.0250568

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