Alkaloid and acetogenin-rich fraction from Annona crassiflora fruit peel inhibits proliferation and migration of human liver cancer HepG2 cells

• Allisson B. Justino,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Institute of Biotechnology, Federal University of Uberlandia, Uberlândia, Minas Gerais, Brazil

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• Rodrigo M. Florentino,

  Roles Conceptualization, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

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• Andressa França,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliations Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil, Department of Molecular Medicine, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

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• Antonio C. M. L. Filho,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

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• Rodrigo R. Franco,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Institute of Biotechnology, Federal University of Uberlandia, Uberlândia, Minas Gerais, Brazil

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• André L. Saraiva,

  Roles Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Institute of Biotechnology, Federal University of Uberlandia, Uberlândia, Minas Gerais, Brazil

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• Matheus C. Fonseca,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliation Brazilian Biosciences National Laboratory (LNBio), Brazilian Center for Research in Energy and Materials (CNPEM), Campinas, São Paulo, Brazil

  https://orcid.org/0000-0001-9048-9775

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• Maria F. Leite,

  Roles Conceptualization, Formal analysis, Funding acquisition, Supervision, Writing – review & editing

  Affiliation Department of Physiology and Biophysics, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

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• Foued Salmen Espindola

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: foued@ufu.br

  Affiliation Institute of Biotechnology, Federal University of Uberlandia, Uberlândia, Minas Gerais, Brazil

  https://orcid.org/0000-0001-7565-1164

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