Abnormal serum chloride is associated with increased mortality among unselected cardiac intensive care unit patients

Thomas J. Breen; Benjamin Brueske; Mandeep S. Sidhu; Kianoush B. Kashani; Nandan S. Anavekar; Gregory W. Barsness; Jacob C. Jentzer

doi:10.1371/journal.pone.0250292

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Open Access

Peer-reviewed

Research Article

Abnormal serum chloride is associated with increased mortality among unselected cardiac intensive care unit patients

Thomas J. Breen,

Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Internal Medicine, Mayo Clinic, Rochester MN, United States of America
⨯
Benjamin Brueske,

Roles Conceptualization, Writing – original draft

Affiliation Division of Cardiology, Department of Medicine, Albany Medical Center and Albany Medical College, Albany, NY, United States of America
⨯
Mandeep S. Sidhu,

Roles Supervision, Writing – review & editing

Affiliation Division of Cardiology, Department of Medicine, Albany Medical Center and Albany Medical College, Albany, NY, United States of America
⨯
Kianoush B. Kashani,

Roles Supervision, Writing – review & editing

Affiliations Division of Nephrology & Hypertension, Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States of America, Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States of America
⨯
Nandan S. Anavekar,

Roles Supervision, Writing – review & editing

Affiliation Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States of America
⨯
Gregory W. Barsness,

Roles Supervision, Writing – review & editing

Affiliation Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States of America
⨯
Jacob C. Jentzer

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: jentzer.jacob@mayo.edu

Affiliations Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Mayo Clinic, Rochester, MN, United States of America, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, United States of America

https://orcid.org/0000-0002-6366-2859

⨯

Abnormal serum chloride is associated with increased mortality among unselected cardiac intensive care unit patients

Thomas J. Breen,
Benjamin Brueske,
Mandeep S. Sidhu,
Kianoush B. Kashani,
Nandan S. Anavekar,
Gregory W. Barsness,
Jacob C. Jentzer

Published: April 26, 2021
https://doi.org/10.1371/journal.pone.0250292

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Chlorides
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Anions
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Death rates
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Acidosis
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Bicarbonates
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Heart failure
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Intensive care units
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Electrolytes
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