Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults

• Tamas Csipo ,

  Contributed equally to this work with: Tamas Csipo, Agnes Lipecz, Peter Mukli

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft

  Affiliations Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Department of Public Health, Semmelweis University, Faculty of Medicine, Budapest, Hungary

  https://orcid.org/0000-0003-2639-2404

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• Agnes Lipecz ,

  Contributed equally to this work with: Tamas Csipo, Agnes Lipecz, Peter Mukli

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft

  Affiliations Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Department of Public Health, Semmelweis University, Faculty of Medicine, Budapest, Hungary, Department of Ophthalmology, Josa Andras Hospital, Nyiregyhaza, Hungary

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• Peter Mukli ,

  Contributed equally to this work with: Tamas Csipo, Agnes Lipecz, Peter Mukli

  Roles Formal analysis

  Affiliations Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Department of Physiology, Semmelweis University, Faculty of Medicine, Budapest, Hungary

  https://orcid.org/0000-0003-4355-8103

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• Dhay Bahadli,

  Roles Conceptualization, Formal analysis

  Affiliation Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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• Osamah Abdulhussein,

  Roles Conceptualization, Formal analysis

  Affiliation Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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• Cameron D. Owens,

  Roles Formal analysis

  Affiliation Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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• Stefano Tarantini,

  Roles Formal analysis, Writing – review & editing

  Affiliation Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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• Rachel A. Hand,

  Roles Data curation

  Affiliation Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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• Valeriya Yabluchanska,

  Roles Formal analysis

  Affiliations Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Bon Secours St. Francis Family Medicine Center, Midlothian, Virginia, United States of America

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• J. Mikhail Kellawan,

  Roles Conceptualization, Formal analysis, Writing – review & editing

  Affiliation Department of Health and Exercise Science, University of Oklahoma, Norman, Oklahoma, United States of America

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• Farzaneh Sorond,

  Roles Formal analysis, Writing – review & editing

  Affiliation Division of Stroke and Neurocritical, Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, United States of America

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• Judith A. James,

  Roles Writing – review & editing

  Affiliations Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Arthritis & Clinical Immunology Research Program, Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma, United States of America

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• Anna Csiszar,

  Roles Conceptualization, Writing – review & editing

  Affiliations Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Department of Medical Physics and Informatics, University of Szeged, Szeged, Hungary

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• Zoltan I. Ungvari,

  Roles Writing – review & editing

  Affiliations Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Department of Public Health, Semmelweis University, Faculty of Medicine, Budapest, Hungary, Department of Medical Physics and Informatics, University of Szeged, Szeged, Hungary, Department of Health Promotion Sciences, College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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• Andriy Yabluchanskiy

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: andriy-yabluchanskiy@ouhsc.edu

  Affiliations Vascular Cognitive Impairment and Neurodegeneration Program, Center for Geroscience and Healthy Brain Aging, Department of Biochemistry and Molecular Biology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Section of Geriatrics, Department of Internal Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

  https://orcid.org/0000-0002-9648-7161

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