Comprehensive profiling of the gut microbiota in patients with chronic obstructive pulmonary disease of varying severity

Yu-Chi Chiu; Shih-Wei Lee; Chi-Wei Liu; Rebecca Chou-Jui Lin; Yung-Chia Huang; Tzuo-Yun Lan; Lawrence Shih-Hsin Wu

doi:10.1371/journal.pone.0249944

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Open Access

Peer-reviewed

Research Article

Comprehensive profiling of the gut microbiota in patients with chronic obstructive pulmonary disease of varying severity

Yu-Chi Chiu ,

Contributed equally to this work with: Yu-Chi Chiu, Shih-Wei Lee

Roles Funding acquisition, Investigation, Writing – original draft

Affiliations Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan, Institute of Hospital & Health Care Administration, National Yang Ming Chiao Tung University, Taipei, Taiwan
⨯
Shih-Wei Lee ,

Contributed equally to this work with: Yu-Chi Chiu, Shih-Wei Lee

Roles Conceptualization, Funding acquisition, Methodology, Writing – original draft

Affiliation Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan
⨯
Chi-Wei Liu,

Roles Investigation, Methodology, Project administration

Affiliation Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan
⨯
Rebecca Chou-Jui Lin,

Roles Investigation, Methodology

Affiliation Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan
⨯
Yung-Chia Huang,

Roles Investigation, Methodology

Affiliation Department of Internal Medicine, Taoyuan General Hospital, Ministry of Health and Welfare, Taoyuan, Taiwan
⨯
Tzuo-Yun Lan ,

Roles Conceptualization, Writing – original draft, Writing – review & editing

* E-mail: lshwu@hotmail.com (LSW); tylan@nycu.edu.tw (TYL)

Affiliation Institute of Hospital & Health Care Administration, National Yang Ming Chiao Tung University, Taipei, Taiwan
⨯
Lawrence Shih-Hsin Wu

Roles Conceptualization, Formal analysis, Investigation, Project administration, Supervision, Writing – original draft, Writing – review & editing

* E-mail: lshwu@hotmail.com (LSW); tylan@nycu.edu.tw (TYL)

Affiliation Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan

https://orcid.org/0000-0001-6275-8368

⨯

Comprehensive profiling of the gut microbiota in patients with chronic obstructive pulmonary disease of varying severity

Yu-Chi Chiu,
Shih-Wei Lee,
Chi-Wei Liu,
Rebecca Chou-Jui Lin,
Yung-Chia Huang,
Tzuo-Yun Lan,
Lawrence Shih-Hsin Wu

Published: April 9, 2021
https://doi.org/10.1371/journal.pone.0249944

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Chronic obstructive pulmonary disease
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Gut bacteria
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Eosinophils
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Microbiome
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Inflammation
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Pulmonary function
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Blood
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Bacterial pathogens
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