Avidity observed between a bivalent inhibitor and an enzyme monomer with a single active site

• Shiran Lacham-Hartman,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft

  Affiliation Avram and Stella Goldstein-Goren Department of Biotechnology Engineering and the National Institute of Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel

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• Yulia Shmidov,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Deprtment of Chemical Engineering and the Ilse Katz Institute for Nanoscale Science & Technology, Ben-Gurion University of the Negev, Beer-Sheva, Israel

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• Evette S. Radisky,

  Roles Funding acquisition, Methodology, Resources, Writing – review & editing

  Affiliation Department of Cancer Biology, Mayo Clinic Comprehensive Cancer Center, Jacksonville, Florida, United States of America

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• Ronit Bitton,

  Roles Formal analysis, Methodology, Writing – review & editing

  Affiliation Deprtment of Chemical Engineering and the Ilse Katz Institute for Nanoscale Science & Technology, Ben-Gurion University of the Negev, Beer-Sheva, Israel

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• David B. Lukatsky ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Validation, Writing – review & editing

  * E-mail: papo@bgu.ac.il (NP); lukatsky@bgu.ac.il (DBL)

  Affiliation Department of Chemistry, Ben-Gurion University of the Negev, Beer-Sheva, Israel

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• Niv Papo

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft

  * E-mail: papo@bgu.ac.il (NP); lukatsky@bgu.ac.il (DBL)

  Affiliation Avram and Stella Goldstein-Goren Department of Biotechnology Engineering and the National Institute of Biotechnology in the Negev, Ben-Gurion University of the Negev, Beer-Sheva, Israel

  https://orcid.org/0000-0002-7056-2418

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