Biophysical characterization and a roadmap towards the NMR solution structure of G0S2, a key enzyme in non-alcoholic fatty liver disease

• Michael W. Moran,

  Roles Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, United States of America, School of Molecular Sciences, Arizona State University, Tempe, AZ, United States of America

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• Elizabeth P. Ramirez,

  Roles Investigation

  Affiliations Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, United States of America, School of Molecular Sciences, Arizona State University, Tempe, AZ, United States of America

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• James D. Zook,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Software, Supervision, Visualization

  Affiliation Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, United States of America

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• Alicia M. Saarinen,

  Roles Investigation

  Affiliations Department of Biochemistry and Molecular Biology, Mayo Clinic in Arizona Scottsdale, AZ, United States of America, Department of Cardiovascular Medicine, Mayo Clinic in Arizona Scottsdale, AZ, United States of America

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• Bobby Baravati,

  Roles Data curation

  Affiliations Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, United States of America, School of Molecular Sciences, Arizona State University, Tempe, AZ, United States of America

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• Matthew R. Goode,

  Roles Investigation

  Affiliations Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, United States of America, School of Molecular Sciences, Arizona State University, Tempe, AZ, United States of America

  https://orcid.org/0000-0001-5923-6753

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• Vasiliki Laloudakis,

  Roles Investigation

  Affiliation Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, United States of America

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• Emily K. Kaschner,

  Roles Investigation

  Affiliations Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, United States of America, School of Molecular Sciences, Arizona State University, Tempe, AZ, United States of America

  https://orcid.org/0000-0003-2045-5494

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• Tien L. Olson,

  Roles Visualization, Writing – review & editing

  Affiliations Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, United States of America, School of Molecular Sciences, Arizona State University, Tempe, AZ, United States of America

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• Felicia M. Craciunescu,

  Roles Resources

  Affiliation Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, United States of America

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• Debra T. Hansen,

  Roles Conceptualization, Investigation, Writing – review & editing

  Affiliations Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, United States of America, Biodesign Center for Innovations in Medicine, Arizona State University, Tempe, AZ, United States of America

  https://orcid.org/0000-0003-4395-8297

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• Jun Liu,

  Roles Conceptualization, Funding acquisition, Project administration

  Affiliation Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, MN, United States of America

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• Petra Fromme

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  * E-mail: PFromme@asu.edu

  Affiliations Biodesign Center for Applied Structural Discovery, Arizona State University, Tempe, AZ, United States of America, School of Molecular Sciences, Arizona State University, Tempe, AZ, United States of America

  https://orcid.org/0000-0002-8850-518X

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