Metabolic and behavioral features of acute hyperpurinergia and the maternal immune activation mouse model of autism spectrum disorder

• Zarazuela Zolkipli-Cunningham ,

  Contributed equally to this work with: Zarazuela Zolkipli-Cunningham, Jane C. Naviaux

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Current address: The Mitochondrial Medicine Frontier Program, The Children’s Hospital of Philadelphia, United States of America

  Affiliations The Mitochondrial and Metabolic Disease Center, University of California, San Diego School of Medicine, San Diego, CA, United States of America, Department of Neurosciences, University of California, San Diego School of Medicine, San Diego, CA, United States of America

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• Jane C. Naviaux ,

  Contributed equally to this work with: Zarazuela Zolkipli-Cunningham, Jane C. Naviaux

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliations The Mitochondrial and Metabolic Disease Center, University of California, San Diego School of Medicine, San Diego, CA, United States of America, Department of Neurosciences, University of California, San Diego School of Medicine, San Diego, CA, United States of America

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• Tomohiro Nakayama,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Current address: Department of Pediatrics, Ibaraki Prefectural University of Health Sciences, Japan

  Affiliations The Mitochondrial and Metabolic Disease Center, University of California, San Diego School of Medicine, San Diego, CA, United States of America, Department of Neurosciences, University of California, San Diego School of Medicine, San Diego, CA, United States of America

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• Charlotte M. Hirsch,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Current address: Huntington Beach, CA, United States of America

  Affiliation Department of Chemistry, University of California, Irvine (UCI), Irvine, CA, United States of America

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• Jonathan M. Monk,

  Roles Data curation, Formal analysis, Software, Validation, Visualization, Writing – review & editing

  Affiliations The Mitochondrial and Metabolic Disease Center, University of California, San Diego School of Medicine, San Diego, CA, United States of America, Department of Medicine, University of California, San Diego School of Medicine, San Diego, CA, United States of America

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• Kefeng Li,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliations The Mitochondrial and Metabolic Disease Center, University of California, San Diego School of Medicine, San Diego, CA, United States of America, Department of Medicine, University of California, San Diego School of Medicine, San Diego, CA, United States of America

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• Lin Wang,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – review & editing

  Affiliations The Mitochondrial and Metabolic Disease Center, University of California, San Diego School of Medicine, San Diego, CA, United States of America, Department of Medicine, University of California, San Diego School of Medicine, San Diego, CA, United States of America

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• Thuy P. Le,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliations The Mitochondrial and Metabolic Disease Center, University of California, San Diego School of Medicine, San Diego, CA, United States of America, Department of Neurosciences, University of California, San Diego School of Medicine, San Diego, CA, United States of America

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• Simone Meinardi,

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Department of Chemistry, University of California, Irvine (UCI), Irvine, CA, United States of America

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• Donald R. Blake,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

  Affiliation Department of Chemistry, University of California, Irvine (UCI), Irvine, CA, United States of America

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• Robert K. Naviaux

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rnaviaux@health.ucsd.edu

  Affiliations The Mitochondrial and Metabolic Disease Center, University of California, San Diego School of Medicine, San Diego, CA, United States of America, Department of Medicine, University of California, San Diego School of Medicine, San Diego, CA, United States of America, Department of Pediatrics, University of California, San Diego School of Medicine, San Diego, CA, United States of America, Department of Pathology, University of California, San Diego School of Medicine, San Diego, CA, United States of America

  https://orcid.org/0000-0001-5832-2297

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