Moringa isothiocyanate-1 regulates Nrf2 and NF-κB pathway in response to LPS-driven sepsis and inflammation

Badi Sri Sailaja; Rohit Aita; Shane Maledatu; David Ribnicky; Michael P. Verzi; Ilya Raskin

doi:10.1371/journal.pone.0248691

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Open Access

Peer-reviewed

Research Article

Moringa isothiocyanate-1 regulates Nrf2 and NF-κB pathway in response to LPS-driven sepsis and inflammation

Badi Sri Sailaja ,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Software, Validation, Visualization, Writing – original draft

* E-mail: raskin@rutgers.edu (IR); sb1747@sebs.rutgers.edu (BSS)

Affiliation Department of Plant Biology, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, United States of America
⨯
Rohit Aita,

Roles Data curation, Formal analysis

Affiliation Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, United States of America

https://orcid.org/0000-0001-5524-9717

⨯
Shane Maledatu,

Roles Data curation, Formal analysis

Affiliation Department of Plant Biology, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, United States of America

https://orcid.org/0000-0002-7506-9657

⨯
David Ribnicky,

Roles Methodology

Affiliation Department of Plant Biology, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, United States of America
⨯
Michael P. Verzi,

Roles Formal analysis, Resources, Supervision, Validation, Visualization, Writing – review & editing

Affiliation Department of Genetics and the Human Genetics Institute of New Jersey, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, United States of America
⨯
Ilya Raskin

Roles Conceptualization, Funding acquisition, Investigation, Project administration, Supervision, Visualization, Writing – review & editing

* E-mail: raskin@rutgers.edu (IR); sb1747@sebs.rutgers.edu (BSS)

Affiliation Department of Plant Biology, School of Environmental and Biological Sciences, Rutgers, The State University of New Jersey, New Brunswick, New Jersey, United States of America

https://orcid.org/0000-0002-3025-8112

⨯

Moringa isothiocyanate-1 regulates Nrf2 and NF-κB pathway in response to LPS-driven sepsis and inflammation

Badi Sri Sailaja,
Rohit Aita,
Shane Maledatu,
David Ribnicky,
Michael P. Verzi,
Ilya Raskin

Published: April 1, 2021
https://doi.org/10.1371/journal.pone.0248691

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