Ischemic stroke in PAR1 KO mice: Decreased brain plasmin and thrombin activity along with decreased infarct volume

Efrat Shavit-Stein; Ekaterina Mindel; Shany Guly Gofrit; Joab Chapman; Nicola Maggio

doi:10.1371/journal.pone.0248431

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Peer-reviewed

Research Article

Ischemic stroke in PAR1 KO mice: Decreased brain plasmin and thrombin activity along with decreased infarct volume

Efrat Shavit-Stein ,

Contributed equally to this work with: Efrat Shavit-Stein, Ekaterina Mindel

Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Visualization, Writing – original draft, Writing – review & editing

* E-mail: efrat.shavit.stein@gmail.com

Affiliations Department of Neurology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Department of Neurology, The Chaim Sheba Medical Center, Ramat Gan, Israel
⨯
Ekaterina Mindel ,

Contributed equally to this work with: Efrat Shavit-Stein, Ekaterina Mindel

Roles Formal analysis, Investigation, Visualization, Writing – review & editing

Affiliations Department of Neurology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Shany Guly Gofrit,

Roles Formal analysis, Investigation, Software, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Neurology, The Chaim Sheba Medical Center, Ramat Gan, Israel

https://orcid.org/0000-0001-6104-606X

⨯
Joab Chapman,

Roles Conceptualization, Formal analysis, Methodology, Supervision, Writing – review & editing

Affiliations Department of Neurology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Department of Neurology, The Chaim Sheba Medical Center, Ramat Gan, Israel, Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Robert and Martha Harden Chair in Mental and Neurological Diseases, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
⨯
Nicola Maggio

Roles Conceptualization, Formal analysis, Methodology, Project administration, Writing – original draft, Writing – review & editing

Affiliations Department of Neurology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Department of Neurology, The Chaim Sheba Medical Center, Ramat Gan, Israel, Sagol School of Neuroscience, Tel Aviv University, Tel Aviv, Israel
⨯

Ischemic stroke in PAR1 KO mice: Decreased brain plasmin and thrombin activity along with decreased infarct volume

Efrat Shavit-Stein,
Ekaterina Mindel,
Shany Guly Gofrit,
Joab Chapman,
Nicola Maggio

Published: March 15, 2021
https://doi.org/10.1371/journal.pone.0248431

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Ischemic stroke
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Central nervous system
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