Identifying treatment options for BRAF^V600 wild-type metastatic melanoma: A SU2C/MRA genomics-enabled clinical trial

• Patricia M. LoRusso ,

  Contributed equally to this work with: Patricia M. LoRusso, Aleksandar Sekulic, Jeffrey A. Sosman

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Yale Cancer Center, Yale University, New Haven, CT, United States of America

  ⨯
• Aleksandar Sekulic ,

  Contributed equally to this work with: Patricia M. LoRusso, Aleksandar Sekulic, Jeffrey A. Sosman

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – review & editing

  Affiliations Mayo Clinic, Scottsdale, AZ, United States of America, Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Jeffrey A. Sosman ,

  Contributed equally to this work with: Patricia M. LoRusso, Aleksandar Sekulic, Jeffrey A. Sosman

  Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Evanston, IL, United States of America

  ⨯
• Winnie S. Liang,

  Roles Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• John Carpten,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America

  ⨯
• David W. Craig,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Resources, Software, Supervision, Writing – review & editing

  Affiliation Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America

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• David B. Solit,

  Roles Investigation, Writing – review & editing

  Affiliation Memorial Sloan Kettering Cancer Center, New York, NY, United States of America

  ⨯
• Alan H. Bryce,

  Roles Investigation, Writing – review & editing

  Affiliation Mayo Clinic, Scottsdale, AZ, United States of America

  ⨯
• Jeffrey A. Kiefer,

  Roles Data curation, Formal analysis, Methodology, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Jessica Aldrich,

  Roles Formal analysis, Methodology, Resources, Software, Visualization, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Sara Nasser,

  Roles Formal analysis, Methodology, Software, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Rebecca Halperin,

  Roles Formal analysis, Investigation, Methodology, Resources, Software, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Sara A. Byron,

  Roles Data curation, Formal analysis, Investigation, Resources, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Mary Jo Pilat,

  Roles Data curation, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, United States of America

  ⨯
• Scott A. Boerner,

  Roles Project administration, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Yale Cancer Center, Yale University, New Haven, CT, United States of America

  ⨯
• Diane Durecki,

  Roles Investigation, Writing – review & editing

  Affiliation Yale Cancer Center, Yale University, New Haven, CT, United States of America

  ⨯
• William P. D. Hendricks,

  Roles Investigation, Project administration, Supervision, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Daniel Enriquez,

  Roles Data curation, Formal analysis, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Tyler Izatt,

  Roles Data curation, Visualization, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Jonathan Keats,

  Roles Methodology, Resources, Software, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Christophe Legendre,

  Roles Formal analysis, Resources, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Svetomir N. Markovic,

  Roles Investigation, Writing – review & editing

  Affiliation Mayo Clinic, Rochester, MN, United States of America

  ⨯
• Amy Weise,

  Roles Investigation, Writing – review & editing

  Affiliation Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, MI, United States of America

  ⨯
• Fatima Naveed,

  Roles Formal analysis, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Jessica Schmidt,

  Roles Investigation, Writing – review & editing

  Affiliation Mayo Clinic, Scottsdale, AZ, United States of America

  ⨯
• Gargi D. Basu,

  Roles Data curation, Investigation, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Shobana Sekar,

  Roles Formal analysis, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Jonathan Adkins,

  Roles Validation, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Erica Tassone,

  Roles Validation, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Karthigayini Sivaprakasam,

  Roles Formal analysis, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Victoria Zismann,

  Roles Project administration, Writing – review & editing

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Valerie S. Calvert,

  Roles Investigation, Writing – review & editing

  Affiliation Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, United States of America

  ⨯
• Emanuel F. Petricoin,

  Roles Formal analysis, Investigation, Methodology, Resources, Writing – original draft, Writing – review & editing

  Affiliation Center for Applied Proteomics and Molecular Medicine, George Mason University, Manassas, VA, United States of America

  ⨯
• Leslie Anne Fecher,

  Roles Investigation

  Affiliation University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, United States of America

  ⨯
• Christopher Lao,

  Roles Investigation

  Affiliation University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI, United States of America

  ⨯
• J. Paul Eder,

  Roles Investigation

  Affiliation Yale Cancer Center, Yale University, New Haven, CT, United States of America

  ⨯
• Nicholas J. Vogelzang,

  Roles Investigation

  Affiliation US Oncology, United States of America

  ⨯
• Jane Perlmutter,

  Roles Resources

  Affiliation Gemini Group, Ann Arbor, MI, United States of America

  ⨯
• Mark Gorman,

  Roles Investigation

  Affiliation Silver Spring, MD, United States of America

  ⨯
• Barbara Manica,

  Roles Investigation

  Affiliation Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, MI, United States of America

  ⨯
• Lisa Fox,

  Roles Project administration

  Affiliation Yale Cancer Center, Yale University, New Haven, CT, United States of America

  ⨯
• Nicholas Schork,

  Roles Investigation

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  ⨯
• Daniel Zelterman,

  Roles Investigation

  Affiliation Yale Cancer Center, Yale University, New Haven, CT, United States of America

  ⨯
• Michelle DeVeaux,

  Roles Investigation

  Affiliations Yale Cancer Center, Yale University, New Haven, CT, United States of America, Regeneron Pharmaceuticals, Tarrytown, NY, United States of America

  ⨯
• Richard W. Joseph,

  Roles Investigation

  Affiliation Mayo Clinic, Jacksonville, FL, United States of America

  ⨯
• C. Lance Cowey,

  Roles Investigation

  Affiliation Charles A. Sammons Cancer Center/Baylor University Medical Center, Dallas, TX, United States of America

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•  [ ... ],
• Jeffrey M. Trent

  Roles Conceptualization, Funding acquisition, Investigation, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: jtrent@tgen.org

  Affiliation Translational Genomics Research Institute, Phoenix, AZ, United States of America

  https://orcid.org/0000-0003-0183-4202

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