A prospective study of the adaptive changes in the gut microbiome during standard-of-care chemoradiotherapy for gynecologic cancers

• Molly B. El Alam ,

  Contributed equally to this work with: Molly B. El Alam, Travis T. Sims

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Software, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Travis T. Sims ,

  Contributed equally to this work with: Molly B. El Alam, Travis T. Sims

  Roles Conceptualization, Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Ramez Kouzy,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Greyson W. G. Biegert,

  Roles Formal analysis, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Joseph A. B. I. Jaoude,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Tatiana V. Karpinets,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Kyoko Yoshida-Court,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Xiaogang Wu,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Andrea Y. Delgado-Medrano,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Melissa P. Mezzari,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Molecular Virology and Microbiology, Alkek Center for Metagenomics and Microbiome Research, Baylor College of Medicine, Houston, TX, United States of America

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• Nadim J. Ajami,

  Roles Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Travis Solley,

  Roles Formal analysis, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Mustapha Ahmed-Kaddar,

  Roles Writing – original draft, Writing – review & editing

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Lilie L. Lin,

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Lois Ramondetta,

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Amir Jazaeri,

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Anuja Jhingran,

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Patricia J. Eifel,

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Kathleen M. Schmeler,

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Jennifer Wargo,

  Roles Conceptualization, Data curation, Writing – original draft, Writing – review & editing

  Affiliation Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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• Ann H. Klopp ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: aklopp@mdanderson.org (AHK); lcolbert@mdanderson.org (LEC)

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

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•  [ ... ],
• Lauren E. Colbert

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: aklopp@mdanderson.org (AHK); lcolbert@mdanderson.org (LEC)

  Affiliation Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, United States of America

  https://orcid.org/0000-0001-5806-4339

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