Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1

Ebtesam Nafie; Jade Lolarga; Brandon Lam; Jonathan Guo; Elnaz Abdollahzadeh; Sandy Rodriguez; Carlotta Glackin; Junjun Liu

doi:10.1371/journal.pone.0247652

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Open Access

Peer-reviewed

Research Article

Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1

Ebtesam Nafie ,

Contributed equally to this work with: Ebtesam Nafie, Jade Lolarga

Roles Data curation, Formal analysis, Investigation, Writing – review & editing

Affiliations Beckman Research Institute, City of Hope, Duarte, CA, United States of America, Zoology Department, Faculty of Sciences, Benha University, Benha, Egypt
⨯
Jade Lolarga ,

Contributed equally to this work with: Ebtesam Nafie, Jade Lolarga

Roles Investigation

Affiliation Department of Biological Sciences, California State Polytechnic University, Pomona, CA, United States of America
⨯
Brandon Lam,

Roles Investigation

Affiliation Department of Biological Sciences, California State Polytechnic University, Pomona, CA, United States of America
⨯
Jonathan Guo,

Roles Data curation, Investigation

Affiliation Department of Biological Sciences, California State Polytechnic University, Pomona, CA, United States of America
⨯
Elnaz Abdollahzadeh,

Roles Investigation

Affiliation Department of Biological Sciences, California State Polytechnic University, Pomona, CA, United States of America
⨯
Sandy Rodriguez,

Roles Investigation

Affiliation Department of Biological Sciences, California State University, Long Beach, CA, United States of America
⨯
Carlotta Glackin ,

Roles Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Writing – review & editing

* E-mail: junjunliu@cpp.edu (JL); cglackin@coh.org (CG)

Affiliation Beckman Research Institute, City of Hope, Duarte, CA, United States of America
⨯
Junjun Liu

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing

* E-mail: junjunliu@cpp.edu (JL); cglackin@coh.org (CG)

Affiliation Department of Biological Sciences, California State Polytechnic University, Pomona, CA, United States of America

https://orcid.org/0000-0002-9427-1113

⨯

Harmine inhibits breast cancer cell migration and invasion by inducing the degradation of Twist1

Ebtesam Nafie,
Jade Lolarga,
Brandon Lam,
Jonathan Guo,
Elnaz Abdollahzadeh,
Sandy Rodriguez,
Carlotta Glackin,
Junjun Liu

Published: February 24, 2021
https://doi.org/10.1371/journal.pone.0247652

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