Pluripotent stem cell model of early hematopoiesis in Down syndrome reveals quantitative effects of short-form GATA1 protein on lineage specification

• Shiori Matsuo,

  Roles Conceptualization, Data curation, Formal analysis, Writing – original draft

  Affiliation Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

  ⨯
• Yoko Nishinaka-Arai ,

  Roles Conceptualization, Data curation, Formal analysis, Project administration, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: yoko@cira.kyoto-u.ac.jp (YNA); akiranw@cira.kyoto-u.ac.jp (AN); msaito@cira.kyoto-u.ac.jp (MKS)

  Affiliations Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan, Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan

  ⨯
• Yasuhiro Kazuki,

  Roles Methodology, Resources

  Affiliations Chromosome Engineering Research Center, Tottori University, Tottori, Japan, Division of Genome and Cellular Functions, Department of Molecular and Cellular Biology, School of Life Science, Faculty of Medicine, Tottori University, Tottori, Japan

  ⨯
• Mitsuo Oshimura,

  Roles Methodology, Resources

  Affiliation Chromosome Engineering Research Center, Tottori University, Tottori, Japan

  ⨯
• Tatsutoshi Nakahata,

  Roles Supervision

  Affiliation Drug Discovery Technology Development Office, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

  ⨯
• Akira Niwa ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: yoko@cira.kyoto-u.ac.jp (YNA); akiranw@cira.kyoto-u.ac.jp (AN); msaito@cira.kyoto-u.ac.jp (MKS)

  Affiliation Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

  https://orcid.org/0000-0002-6412-2686

  ⨯
• Megumu K. Saito

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: yoko@cira.kyoto-u.ac.jp (YNA); akiranw@cira.kyoto-u.ac.jp (AN); msaito@cira.kyoto-u.ac.jp (MKS)

  Affiliation Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University, Kyoto, Japan

  ⨯