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Open Access
Peer-reviewed
Research Article
Suppressive effects of vitamin C-treated induced-regulatory T cells on heart allograft rejection under vitamin C-deficient or –sufficient conditions
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Ju Hee Hwang ,
Contributed equally to this work with: Ju Hee Hwang, Honglin Piao
Roles Investigation, Writing – original draft
Affiliation Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea
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Honglin Piao ,
Contributed equally to this work with: Ju Hee Hwang, Honglin Piao
Roles Investigation, Writing – original draft
Affiliations Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea, Department of Medicine, Graduate School, Seoul National University College of Medicine, Seoul, Republic of Korea
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Joon Young Jang,
Roles Investigation
Affiliation Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea
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Sun-Kyung Lee,
Roles Investigation
Affiliations Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea, Department of Medicine, Graduate School, Seoul National University College of Medicine, Seoul, Republic of Korea
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Dongkyu Han,
Roles Investigation
Affiliation Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea
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Gwang-Min Lee,
Roles Investigation
Affiliation Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea
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Cheolhyeon Go,
Roles Investigation
Affiliation Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul, Republic of Korea
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Yejin Kim,
Roles Investigation
Affiliations Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul, Republic of Korea, Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul, Republic of Korea
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Kwon Ik Oh,
Roles Conceptualization, Supervision, Writing – review & editing
Affiliation Department of Pathology, Hallym University College of Medicine, Chuncheon, Republic of Korea
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Jae Seung Kang,
Roles Supervision, Writing – review & editing
Affiliations Department of Anatomy and Cell Biology, Seoul National University College of Medicine, Seoul, Republic of Korea, Institute of Allergy and Clinical Immunology, Seoul National University Medical Research Center, Seoul, Republic of Korea
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Ji-Jing Yan ,
Roles Conceptualization, Data curation, Investigation, Writing – review & editing
* E-mail: jcyjs@snu.ac.kr (JY); jjyanpharm@gmail.com (J-JY)
Affiliation Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea
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Jaeseok Yang
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Writing – review & editing
* E-mail: jcyjs@snu.ac.kr (JY); jjyanpharm@gmail.com (J-JY)
Affiliations Transplantation Center, Seoul National University Hospital, Seoul, Republic of Korea, Department of surgery, Seoul National University hospital, Seoul, Republic of Korea
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Suppressive effects of vitamin C-treated induced-regulatory T cells on heart allograft rejection under vitamin C-deficient or –sufficient conditions
- Ju Hee Hwang,
- Honglin Piao,
- Joon Young Jang,
- Sun-Kyung Lee,
- Dongkyu Han,
- Gwang-Min Lee,
- Cheolhyeon Go,
- Yejin Kim,
- Kwon Ik Oh,
- Jae Seung Kang
- Published: February 12, 2021
- https://doi.org/10.1371/journal.pone.0246967