Enzymatically polymerised polyphenols prepared from various precursors potentiate antigen-specific immune responses in both mucosal and systemic compartments in mice

• Rui Tada ,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Visualization, Writing – original draft

  * E-mail: rui.tada@gmail.com

  Affiliation Department of Drug Delivery and Molecular Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

  https://orcid.org/0000-0003-0098-9587

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• Miki Ogasawara,

  Roles Data curation, Formal analysis

  Affiliation Department of Drug Delivery and Molecular Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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• Daisuke Yamanaka,

  Roles Conceptualization, Data curation, Methodology, Writing – review & editing

  Affiliation Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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• Yasuhiro Sakurai,

  Roles Data curation

  Affiliation Department of Drug Delivery and Molecular Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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• Yoichi Negishi,

  Roles Funding acquisition, Resources

  Affiliation Department of Drug Delivery and Molecular Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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• Hiroshi Kiyono,

  Roles Methodology, Resources

  Affiliation Division of Mucosal Immunology and International Research and Development Center for Mucosal Vaccines, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan

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• Naohito Ohno,

  Roles Funding acquisition, Resources

  Affiliation Laboratory for Immunopharmacology of Microbial Products, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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• Jun Kunisawa,

  Roles Formal analysis, Funding acquisition, Writing – review & editing

  Affiliations Division of Mucosal Immunology and International Research and Development Center for Mucosal Vaccines, Department of Microbiology and Immunology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan, Laboratory of Vaccine Materials and Laboratory of Gut Environmental System, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Osaka, Japan

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• Yukihiko Aramaki

  Roles Funding acquisition, Project administration, Supervision, Writing – review & editing

  Affiliation Department of Drug Delivery and Molecular Biopharmaceutics, School of Pharmacy, Tokyo University of Pharmacy and Life Sciences, Tokyo, Japan

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