In vitro study of Hesperetin and Hesperidin as inhibitors of zika and chikungunya virus proteases

• Raphael J. Eberle ,

  Contributed equally to this work with: Raphael J. Eberle, Monika A. Coronado

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Writing – original draft

  * E-mail: r.eberle@fz-juelich.de (RJE); m.coronado@fz-juelich.de (MAC)

  Affiliations Multiuser Center for Biomolecular Innovation, Departament of Physics, Instituto de Biociências Letras e Ciências Exatas (Ibilce), Universidade Estadual Paulista (UNESP), São Jose do Rio Preto, SP, Brazil, Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, Jülich, Germany

  https://orcid.org/0000-0002-8763-3884

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• Danilo S. Olivier,

  Roles Investigation, Software, Validation

  Affiliation Federal University of Tocantins, Araguaína, TO, Brazil

  https://orcid.org/0000-0003-1269-3783

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• Carolina C. Pacca,

  Roles Formal analysis, Investigation, Methodology, Validation

  Affiliations Instituto de Biociências Letras e Ciências Exatas (Ibilce), Universidade Estadual Paulista (UNESP), São Jose do Rio Preto, SP, Brazil, FACERES Medical School, São José do Rio Preto, Brazil

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• Clarita M. S. Avilla,

  Roles Investigation, Methodology

  Affiliation Instituto de Biociências Letras e Ciências Exatas (Ibilce), Universidade Estadual Paulista (UNESP), São Jose do Rio Preto, SP, Brazil

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• Mauricio L. Nogueira,

  Roles Formal analysis, Resources

  Affiliation Faculdade de Medicina de São José do Rio Preto–FAMERP, São José do Rio Preto, Brazil

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• Marcos S. Amaral,

  Roles Investigation, Software, Validation

  Affiliation Institute of Physics, Federal University of Mato Grosso do Sul, Campo Grande, MS, Brazil

  https://orcid.org/0000-0001-8101-6933

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• Dieter Willbold,

  Roles Resources, Writing – review & editing

  Affiliations Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, Jülich, Germany, Institut für Physikalische Biologie, Heinrich-Heine-Universität Düsseldorf, Universitätsstraße, Düsseldorf, Germany, JuStruct: Jülich Centre for Structural Biology, Forchungszentrum Jülich, Jülich, Germany

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• Raghuvir K. Arni,

  Roles Resources, Writing – review & editing

  Affiliation Multiuser Center for Biomolecular Innovation, Departament of Physics, Instituto de Biociências Letras e Ciências Exatas (Ibilce), Universidade Estadual Paulista (UNESP), São Jose do Rio Preto, SP, Brazil

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• Monika A. Coronado

  Contributed equally to this work with: Raphael J. Eberle, Monika A. Coronado

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Supervision, Validation, Writing – review & editing

  * E-mail: r.eberle@fz-juelich.de (RJE); m.coronado@fz-juelich.de (MAC)

  Affiliations Multiuser Center for Biomolecular Innovation, Departament of Physics, Instituto de Biociências Letras e Ciências Exatas (Ibilce), Universidade Estadual Paulista (UNESP), São Jose do Rio Preto, SP, Brazil, Institute of Biological Information Processing (IBI-7: Structural Biochemistry), Forschungszentrum Jülich, Jülich, Germany

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