Identification of Prostaglandin F2 Receptor Negative Regulator (PTGFRN) as an internalizable target in cancer cells for antibody-drug conjugate development

• Jorge Marquez ,

  Contributed equally to this work with: Jorge Marquez

  Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliations Target Discovery Division, A&G Pharmaceutical, Inc., Columbia, Maryland, United States of America, Department of Pharmaceutical Sciences, University of Maryland, Baltimore School of Pharmacy, Baltimore, Maryland, United States of America

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• Jianping Dong ,

  Roles Data curation, Investigation, Methodology, Validation

  ¶‡ JD, CD and CT also contributed equally to this work.

  Affiliation Target Discovery Division, A&G Pharmaceutical, Inc., Columbia, Maryland, United States of America

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• Chun Dong ,

  Roles Investigation, Methodology, Resources

  ¶‡ JD, CD and CT also contributed equally to this work.

  Affiliation Precision Antibody Division, A&G Pharmaceutical, Inc., Columbia, Maryland, United States of America

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• Changsheng Tian ,

  Roles Investigation, Methodology, Validation

  ¶‡ JD, CD and CT also contributed equally to this work.

  Affiliation Target Discovery Division, A&G Pharmaceutical, Inc., Columbia, Maryland, United States of America

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• Ginette Serrero

  Roles Conceptualization, Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: gserrero@agpharma.com

  Affiliations Target Discovery Division, A&G Pharmaceutical, Inc., Columbia, Maryland, United States of America, Precision Antibody Division, A&G Pharmaceutical, Inc., Columbia, Maryland, United States of America

  https://orcid.org/0000-0003-3607-0273

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