Early prognostic performance of miR155-5p monitoring for the risk of rejection: Logistic regression with a population pharmacokinetic approach in adult kidney transplant patients

• Luis Quintairos ,

  Contributed equally to this work with: Luis Quintairos, Helena Colom

  Roles Formal analysis, Methodology, Writing – original draft

  Affiliations Faculty of Pharmacy and Food Sciences, Biopharmaceutics and Pharmacokinetics Unit, Department of Pharmacy, Pharmaceutical Technology and Physical Chemistry, University of Barcelona, Barcelona, Spain, Pharmacology and Toxicology Laboratory, Biochemistry and Molecular Genetics, Biomedical Diagnostic Center (CDB), Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain

  https://orcid.org/0000-0002-9133-350X

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• Helena Colom ,

  Contributed equally to this work with: Luis Quintairos, Helena Colom

  Roles Conceptualization, Methodology, Supervision, Writing – original draft

  * E-mail: helena.colom@ub.edu

  Affiliation Faculty of Pharmacy and Food Sciences, Biopharmaceutics and Pharmacokinetics Unit, Department of Pharmacy, Pharmaceutical Technology and Physical Chemistry, University of Barcelona, Barcelona, Spain

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• Olga Millán,

  Roles Investigation, Writing – review & editing

  Affiliations Pharmacology and Toxicology Laboratory, Biochemistry and Molecular Genetics, Biomedical Diagnostic Center (CDB), Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain, Biomedical Research Center in Hepatic and Digestive Diseases (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain

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• Virginia Fortuna,

  Roles Investigation

  Affiliation Pharmacology and Toxicology Laboratory, Biochemistry and Molecular Genetics, Biomedical Diagnostic Center (CDB), Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain

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• Cristina Espinosa,

  Roles Investigation

  Affiliation Pharmacology and Toxicology Laboratory, Biochemistry and Molecular Genetics, Biomedical Diagnostic Center (CDB), Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain

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• Lluis Guirado,

  Roles Project administration, Resources

  Affiliation Renal Transplant Unit, Nephrology Department, Fundació Puigvert, Barcelona, Spain

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• Klemens Budde,

  Roles Project administration, Resources

  Affiliation Medizinische Klinik mit Schwerpunkt Nephrologie, Charité Universitätsmedizin Berlin, Berlin, Germany

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• Claudia Sommerer,

  Roles Project administration, Resources

  Affiliation Department of Nephrology, University of Heidelberg, University Hospital of Heidelberg and Mannheim, Heidelberg, Germany

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• Ana Lizana,

  Roles Investigation

  Affiliation Pharmacology and Toxicology Laboratory, Biochemistry and Molecular Genetics, Biomedical Diagnostic Center (CDB), Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain

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• Yolanda López-Púa,

  Roles Validation

  Affiliation Quality Unit of CDB, Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain

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• Mercè Brunet

  Roles Conceptualization, Project administration, Resources, Supervision, Writing – review & editing

  Affiliations Pharmacology and Toxicology Laboratory, Biochemistry and Molecular Genetics, Biomedical Diagnostic Center (CDB), Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain, Biomedical Research Center in Hepatic and Digestive Diseases (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain

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