CD44 modulates metabolic pathways and altered ROS-mediated Akt signal promoting cholangiocarcinoma progression

• Malinee Thanee,

  Roles Conceptualization, Data curation, Investigation, Methodology, Writing – original draft

  Affiliations Cholangiocarcinoma Screening and Care Program (CASCAP), Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand, Department of Pathology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Hasaya Dokduang,

  Roles Methodology

  Affiliations Cholangiocarcinoma Screening and Care Program (CASCAP), Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand

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• Yingpinyapat Kittirat,

  Roles Methodology

  Affiliations Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand, Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Jutarop Phetcharaburanin,

  Roles Formal analysis, Software

  Affiliations Cholangiocarcinoma Screening and Care Program (CASCAP), Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand, Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Poramate Klanrit,

  Roles Writing – review & editing

  Affiliations Cholangiocarcinoma Screening and Care Program (CASCAP), Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand, Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Attapol Titapun,

  Roles Resources, Writing – review & editing

  Affiliations Cholangiocarcinoma Screening and Care Program (CASCAP), Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand, Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Nisana Namwat,

  Roles Writing – review & editing

  Affiliations Cholangiocarcinoma Screening and Care Program (CASCAP), Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand, Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Narong Khuntikeo,

  Roles Resources, Writing – review & editing

  Affiliations Cholangiocarcinoma Screening and Care Program (CASCAP), Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand, Department of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Arporn Wangwiwatsin,

  Roles Writing – review & editing

  Affiliations Cholangiocarcinoma Screening and Care Program (CASCAP), Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand, Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

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• Hideyuki Saya,

  Roles Supervision, Writing – review & editing

  Affiliation Division of Gene Regulation, Institute for Advanced Medical Research (IAMR), Keio University School of Medicine, Tokyo, Japan

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• Watcharin Loilome

  Roles Conceptualization, Data curation, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: watclo@kku.ac.th

  Affiliations Cholangiocarcinoma Screening and Care Program (CASCAP), Khon Kaen University, Khon Kaen, Thailand, Cholangiocarcinoma Research Institute, Khon Kaen University, Khon Kaen, Thailand, Department of Biochemistry, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand

  https://orcid.org/0000-0001-8572-5577

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