Direct antiviral agents for hepatitis C and drug interaction risk: A retrospective cohort study with real and simulated data on medication interaction, prevalence of comorbidities and comedications

• Raquel Boff da Costa ,

  Contributed equally to this work with: Raquel Boff da Costa, Mario Reis Álvares-da-Silva

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: rbdacosta@hcpa.edu.br

  Affiliation Graduate Program Sciences in Gastroenterology and Hepatology, School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil

  https://orcid.org/0000-0002-1665-8208

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• Marisa Boff Costa,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Writing – review & editing

  Affiliation Graduate Program Sciences in Gastroenterology and Hepatology, School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil

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• Larisse Longo,

  Roles Data curation, Formal analysis, Methodology, Resources

  Affiliations Graduate Program Sciences in Gastroenterology and Hepatology, School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil, Experimental Gastroenterology and Hepatology Laboratory, Center for Experimental Research, HCPA, Porto Alegre, Brazil

  https://orcid.org/0000-0002-4453-7227

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• Daniela Elisa Miotto,

  Roles Data curation, Methodology, Validation, Writing – original draft, Writing – review & editing

  Affiliation Gastroenterology Division, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil

  ⨯
• Gustavo Hirata Dellavia,

  Roles Conceptualization, Data curation, Investigation

  Affiliation Gastroenterology Division, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil

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• Matheus Trucollo Michalczuk,

  Roles Conceptualization, Validation

  Affiliations Graduate Program Sciences in Gastroenterology and Hepatology, School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil, Gastroenterology Division, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil

  ⨯
• Mario Reis Álvares-da-Silva

  Contributed equally to this work with: Raquel Boff da Costa, Mario Reis Álvares-da-Silva

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Graduate Program Sciences in Gastroenterology and Hepatology, School of Medicine, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil, Experimental Gastroenterology and Hepatology Laboratory, Center for Experimental Research, HCPA, Porto Alegre, Brazil, Gastroenterology Division, Hospital de Clínicas de Porto Alegre (HCPA), Porto Alegre, Brazil

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