Single nucleotide polymorphism leads to daptomycin resistance causing amino acid substitution—T345I in MprF of clinically isolated MRSA strains

• Masaki Nakamura ,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: m-nakamu@kitasato-u.ac.jp

  Affiliations Department of Microbiology, Kitasato University School of Allied Health Sciences, Kanagawa, Japan, Department of Environmental Microbiology, Kitasato University Graduate School of Medical Sciences, Kanagawa, Japan, Research Center for Infection control, Kitasato Institute for Life Sciences, Kitasato University, Tokyo, Japan

  https://orcid.org/0000-0003-1859-2342

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• Hayato Kawada,

  Roles Investigation, Methodology, Writing – review & editing

  Affiliation Department of Environmental Microbiology, Kitasato University Graduate School of Medical Sciences, Kanagawa, Japan

  ⨯
• Hiroki Uchida,

  Roles Investigation

  Affiliation Department of Microbiology, Kitasato University School of Allied Health Sciences, Kanagawa, Japan

  ⨯
• Yusuke Takagi,

  Roles Investigation

  Affiliation Department of Microbiology, Kitasato University School of Allied Health Sciences, Kanagawa, Japan

  ⨯
• Shuichi Obata,

  Roles Investigation

  Affiliations Department of Anatomical Sciences, Kitasato University School of Allied Health Sciences, Kanagawa, Japan, Department of Histology and Cell Biology, Yokohama City University School of Medicine, Kanagawa, Japan

  ⨯
• Ryotaro Eda,

  Roles Investigation

  Affiliation Department of Environmental Microbiology, Kitasato University Graduate School of Medical Sciences, Kanagawa, Japan

  https://orcid.org/0000-0002-6713-9256

  ⨯
• Hideaki Hanaki,

  Roles Conceptualization, Project administration, Resources, Supervision

  Affiliation Research Center for Infection control, Kitasato Institute for Life Sciences, Kitasato University, Tokyo, Japan

  ⨯
• Hidero Kitasato

  Roles Conceptualization, Project administration, Supervision, Writing – review & editing

  Affiliations Department of Microbiology, Kitasato University School of Allied Health Sciences, Kanagawa, Japan, Department of Environmental Microbiology, Kitasato University Graduate School of Medical Sciences, Kanagawa, Japan

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