In situ kinetic measurements of α-synuclein aggregation reveal large population of short-lived oligomers

• Enrico Zurlo,

  Roles Conceptualization, Data curation, Investigation, Visualization, Writing – original draft

  Affiliation Department of Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Leiden, The Netherlands

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• Pravin Kumar,

  Roles Data curation, Formal analysis, Investigation

  Affiliation Department of Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Leiden, The Netherlands

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• Georg Meisl,

  Roles Formal analysis, Methodology, Visualization, Writing – review & editing

  Affiliation Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, United Kingdom

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• Alexander J. Dear,

  Roles Formal analysis, Methodology, Visualization

  Affiliation Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, United Kingdom

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• Dipro Mondal,

  Roles Formal analysis, Investigation

  Affiliation Department of Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Leiden, The Netherlands

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• Mireille M. A. E. Claessens,

  Roles Resources, Supervision, Writing – review & editing

  Affiliation Nanobiophysics Group, Department of Science and Technology, University Twente, Enschede, The Netherlands

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• Tuomas P. J. Knowles,

  Roles Formal analysis, Resources

  Affiliations Centre for Misfolding Diseases, Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, United Kingdom, Cavendish Laboratory, University of Cambridge, Cambridge, United Kingdom

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• Martina Huber

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Resources, Supervision, Writing – original draft

  * E-mail: huber@physics.leidenuniv.nl

  Affiliation Department of Physics, Huygens-Kamerlingh Onnes Laboratory, Leiden University, Leiden, The Netherlands

  https://orcid.org/0000-0001-7632-1968

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