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CTLA-4 blockade and interferon-α induce proinflammatory transcriptional changes in the tumor immune landscape that correlate with pathologic response in melanoma
- Arjun Khunger,
- Erin Piazza,
- Sarah Warren,
- Thomas H. Smith,
- Xing Ren,
- Andrew White,
- Nathan Elliott,
- Alessandra Cesano,
- Joseph M. Beechem,
- John M. Kirkwood,
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Ahmad A. Tarhini
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing
* E-mail: Ahmad.Tarhini@moffitt.org
Affiliations Department of Cutaneous Oncology and Immunology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States of America, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America
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https://orcid.org/0000-0002-3193-9702
CTLA-4 blockade and interferon-α induce proinflammatory transcriptional changes in the tumor immune landscape that correlate with pathologic response in melanoma
- Arjun Khunger,
- Erin Piazza,
- Sarah Warren,
- Thomas H. Smith,
- Xing Ren,
- Andrew White,
- Nathan Elliott,
- Alessandra Cesano,
- Joseph M. Beechem,
- John M. Kirkwood
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- Published: January 11, 2021
- https://doi.org/10.1371/journal.pone.0245287